Impact of adjuvant radiation therapy photon energy on quality of life after breast conservation therapy: Linear accelerator versus the cobalt machine

Munshi, Anusheel; Dutta, Debnarayan; Budrukkar, Ashwini; Jalali, Rakesh; Sarin, Rajiv; Gupta, Sudeep; Ghosh, Jaya; Bajpai, Jyoti; Parmar, Vani; Nair, Nita; Badwe, Rajendra

doi:10.4103/0973-1482.103513

Cited by 7 publications

(1 citation statement)

References 22 publications

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“…Munshi et al, based in Mumbai, compared the quality of life of patients treated on Cobalt-60 machines versus those treated on linear accelerators and found no difference in outcome. 11 Development of Cobalt-60 technology in modern radiation therapy is slowly making space for more conformal treatment. 12 Despite the growing pressures to abandon use of Cobalt-60 radiotherapy machines, their reliability and relatively easier maintenance remain an attractive option for developing countries in sub-Saharan Africa.…”

Section: Discussionmentioning

confidence: 99%

Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution

Heunis

Lombe

McCaul

2018

Southern African Journal of Gynaecological Oncology

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Breast cancer is the most commonly diagnosed cancer worldwide. With the challenges of cancer treatment in developing countries there is a need for a systematic and methodical approach to treatment in resource-limited settings. Objective: To retrospectively evaluate the profile of breast cancer patients irradiated with curative intent and discuss the therapeutic outcomes, and to compare this cohort with the available developed-world data. Methods: A retrospective cohort of 689 breast cancer patients from 2010-2014 at Tygerberg Hospital, Western Cape Province was analysed. The best-case disease-free survival was calculated at five years and compared with the SEER database. Various prognostic factors were calculated by univariate and multivariate analysis. Results: The five-year best-case disease-free survival (DFS) for Stage I is 94.7% (95% CI 68-99) and for Stage IIIC, 71.3% (95% CI 39-88). Conclusion: Outcomes of treatment at this institution are comparable to data reported in first-world countries. As twodimensional radiotherapy compares with most Cobalt specifications, the majority of breast cancer patients in sub-Saharan Africa can be treated efficiently with Cobalt-type technology.

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Section: Discussionmentioning

confidence: 99%