Impact of acute high-intensity interval exercise on plasma pentraxin 3 and endothelial function in obese individuals—a pilot study

Slusher, Aaron L.; Fico, Brandon G.; Dodge, Katelyn M.; Garten, Ryan S.; Ferrandi, Peter J.; Rodriguez, Alexandra L.; Pena, Gabriel S.; Huang, Chun-Jung

doi:10.1007/s00421-021-04632-5

Cited by 7 publications

(9 citation statements)

References 49 publications

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“…Exercise improved EC function (52) or reversed ED (53). Calorie restriction improved vascular insulin sensitivity and reduced inflammation (54).…”

Section: Lifestyle Interventionmentioning

confidence: 99%

“…ED directly impairs basic vascular function (e.g., blood flow alteration), which made it a great target for pharmacological and/or exercise intervention with insulin-based therapies ( 57 ). Obese individuals who performed an acute high-intensity interval exercise presented with improved plasma pentraxin 3 and endothelial function ( 52 ). Even a short-term weight loss could reverse obesity-induced microvascular ED ( 53 ).…”

Section: Targeting At-ec Axis To Treat Obesity-induced Ed/cvdmentioning

confidence: 99%

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Adipose Tissue-Endothelial Cell Interactions in Obesity-Induced Endothelial Dysfunction

Qian

Kyler

et al. 2021

Front. Cardiovasc. Med.

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Obesity has a strong impact on the pathogenesis of cardiovascular disease, which raises enthusiasm to understand how excess adiposity causes vascular injury. Adipose tissue is an essential regulator of cardiovascular system through its endocrine and paracrine bioactive products. Obesity induces endothelial dysfunction, which often precedes and leads to the development of cardiovascular diseases. Connecting adipose tissue-endothelial cell interplay to endothelial dysfunction may help us to better understand obesity-induced cardiovascular disease. This Mini Review discussed (1) the general interactions and obesity-induced endothelial dysfunction, (2) potential targets, and (3) the outstanding questions for future research.

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“…Exercise improved EC function (52) or reversed ED (53). Calorie restriction improved vascular insulin sensitivity and reduced inflammation (54).…”

Section: Lifestyle Interventionmentioning

confidence: 99%

Section: Targeting At-ec Axis To Treat Obesity-induced Ed/cvdmentioning

confidence: 99%

Adipose Tissue-Endothelial Cell Interactions in Obesity-Induced Endothelial Dysfunction

Qian

Kyler

et al. 2021

Front. Cardiovasc. Med.

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“…Obese people have dysregulated circulating PTX3 levels, which are raised after acute aerobic activity. In patients with CVD, high-intensity interval exercise (HIIE) has been shown to be equally beneficial as continuous moderate-intensity exercise in increasing endothelial function, as measured by BAFMD (brachial artery flow-mediated dilation) [13]. In obese people, HIIE could be used as a time-saving exercise prescription technique to enhance endothelial function in the short term, even if plasma PTX3 levels are elevated [13].…”

Section: Editorialmentioning

confidence: 99%

“…In patients with CVD, high-intensity interval exercise (HIIE) has been shown to be equally beneficial as continuous moderate-intensity exercise in increasing endothelial function, as measured by BAFMD (brachial artery flow-mediated dilation) [13]. In obese people, HIIE could be used as a time-saving exercise prescription technique to enhance endothelial function in the short term, even if plasma PTX3 levels are elevated [13]. Another, the presence of elevated PTX-3 levels in the blood is linked to intermediate to severe obstructive sleep apnea syndrome [14].…”

Section: Editorialmentioning

confidence: 99%

"Is Pentraxin 3 A Marker in Pathogenesis of Metabolic Syndrome?"

Finelli¹

2021

BJSTR

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“…As you can see from this graph, the amount of oxygenated hemoglobin changes continues to decrease after the subjects reach the end point until they reach a minimum and then slowly return to normal levels. 8,9 We then conducted sports tests on dozens of people in a certain university,Almost all athletes with good training level showed similar phenomenon. Example Figure 3.…”

Section: Changes Of Tissue Oxygen After High-intensity Runningmentioning

confidence: 99%

Cardiovascular Control Responses in High Intensity Exercise Stress Tests

Qing-zhong

2021

Rev Bras Med Esporte

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Introduction: High intensity exercise is an important factor to achieve the best exercise effect, and is closely related to the patient's safety and rehabilitation. Objective: To investigate the effects of high intensity exercise on cardiovascular response and substance and energy metabolism. Methods: 50 male students at a university were selected. The average age of the subjects was 23 years old. Process of the experiment: Before the experiment, each subject took routine warm-up activities first, then put on the experimental equipment and began to run 100 meters. At the same time, the subjects’ heart rate, blood oxygen parameters and exercise time were recorded. After passing the finish line, a period of heart rate recording and blood oxygen parameters were continued. Results: Anaerobic metabolism was the main activity in the 100m race. The first 7s after the start of the race, there is a non-lactic acid process without oxygen metabolism, and the muscle oxygen saturation curve presents little change. Conclusions: High intensity exercise in sports training and physical exercise can lead to reduced heart rate variability. The increased incidence of various arrhythmias should be based on the actual situation of the movement of the object, and a reasonable arrangement of exercise load intensity. Level of evidence II; Therapeutic studies - investigation of treatment results.

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Impact of acute high-intensity interval exercise on plasma pentraxin 3 and endothelial function in obese individuals—a pilot study

Cited by 7 publications

References 49 publications

Adipose Tissue-Endothelial Cell Interactions in Obesity-Induced Endothelial Dysfunction

Adipose Tissue-Endothelial Cell Interactions in Obesity-Induced Endothelial Dysfunction

"Is Pentraxin 3 A Marker in Pathogenesis of Metabolic Syndrome?"

Cardiovascular Control Responses in High Intensity Exercise Stress Tests

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