“…Animal experiments have confirmed the benefit of PCs in regulating blood lipids (Li et al, 2019; Rodríguez‐Pérez et al, 2019; Rong et al, 2018). Moreover, several prospective studies (Anderson et al, 2015; Koutsos et al, 2020) and randomized controlled clinical trials (RCTs) (Aihong, 2011; Akazome et al, 2010; Baba et al, 2021; Baba, Natsume, et al, 2007; Baba, Osakabe, et al, 2007; Dianjuan, 2008; Giovannelli et al, 2011; Gupta et al, 2012; Hailin, 2018; Hollands et al, 2018; Hoshino et al, 2019; Jingru, 2012; Novotny et al, 2015; Rodriguez‐Mateos et al, 2018; Sano et al, 2007; Valls et al, 2016; Vigna et al, 2003) have investigated the effect of PCs on blood lipids in normal and mildly hyperlipidemic populations. Some RCTs have demonstrated the regulation of blood lipids by PCs (Baba, Natsume, et al, 2007; Baba, Osakabe, et al, 2007; Gupta et al, 2012; Novotny et al, 2015; Rodriguez‐Mateos et al, 2018; Sano et al, 2007; Valls et al, 2016), whereas others found no significant effect or the opposite effect (Akazome et al, 2010; Hoshino et al, 2019).…”