Impact of abnormal nocturnal blood pressure fall on vascular function

Abstract

Microalbuminuria, an index of vascular function, differentiates reverse dippers from nondippers, but not extreme dippers from dippers among hypertensive patients.

Circadian blood pressure variation: relationship between dipper status and measures of arterial stiffness

“…Additionally, reverse dippers have been shown to have significantly more Dipper status and arterial stiffness Jerrard-Dunne 1237 Pulse wave velocity according to night : day blood pressure ratio categorized into 5% bands rather than arbitrary definitions. microalbuminuria, an index of vascular function [22]. Furthermore, the observed J-shaped relationship between PWV and dipper status in this study mirrors that observed between dipper status and the incidence of both silent cerebral infarcts and clinical stroke [15].…”

Reproducibility of dipping/nondipping pattern in untreated essential hypertensive patients: impact of sex and age

“…It has been reported that nocturnal BP is superior than awake BP as a prognostic predictor of cardiovascular morbidity and mortality in both normotensive and hypertensive individuals [5,6] and that a blunted fall in night-time BP may be related to an increase in target organ damage and cardiovascular events [7][8][9][10]. The clinical and prognostic value of the nondipping pattern, defined as a decline in nocturnal BP less than 10% compared to daytime values [11], however, remains a source of controversial debate as the association between nondipping status and excess of organ damage or cardiovascular events reported by previous studies has not been confirmed by others [12][13][14].…”

Blood pressure variability: Epidemiological and clinical issues

“…Those fi ndings have been confi rmed recently by Ivanovic et al [68]. Patients with abnormal diurnal BP variation patterns (non-dippers, extreme dippers and reverse dippers) have also showed higher plasma BNP levels than those with normal BPV [69] and reverse dippers had higher microalbumin and micoglobulin excretion, and albumin/creatinine ratio [70].…”