Impact of a transition to more restrictive drug formulary on therapy discontinuation and medication adherence

Abstract

Transition of patients to a more restrictive drug formulary led to modest therapy discontinuation, similarly modest improvements in medication adherence and substantial prescription drug cost savings. As healthcare payors search for ways to control the rapid rise in spending for medications without compromising quality, the Value Formulary can serve as a useful tool.

Real-world effectiveness, adherence and persistence among patients with type 2 diabetes mellitus initiating dulaglutide treatment

“…Not surprisingly, as patient out-of-pocket costs increase, adherence decreases 6,11,[40][41][42] . Restrictions put in place by commercial health plans limiting quantities or requiring prior authorization for specific classes of drugs, including GLP-1 RAs, may also affect adherence 43,44 .…”

The Effect of Florida Medicaid’s State-Mandated Formulary Provision on Prescription Drug Use and Health Plan Costs in a Medicaid Managed Care Plan

“…19,20 Some studies have found positive effects of these tools and strategies on pharmacotherapy outcomes. 21,22 Additional research is needed to better understand the effect of state-mandated formularies, inclusive of federal and supplemental rebates that states receive from drug manufacturers. However, we can infer from this study that unintended consequences of decreased drug use and increased costs may result when participating Medicaid plans are unable to leverage utilization management strategies, including MCO managed formularies, to control costs and advocate for appropriate, cost-effective therapy.…”

Évaluation du niveau d’aisance d’étudiants en pharmacie face à la validation des ordonnances. Intérêt d’un dispositif didactique contextualisé

“…Toutefois, le E1 15 39 46 36 53 11 50 35 15 19 42 39 16 55 29 E2 28 36 36 39 46 15 51 35 14 63 29 8 59 32 9 E3 25 40 35 36 46 18 53 31 16 23 38 39 22 39 39 E4 40 39 21 40 48 12 41 34 25 37 44 19 35 46 19 E5 28 43 29 40 54 6 69 24 7 41 49 10 42 44 14 E6 14 35 51 47 42 11 54 36 10 35 43 22 34 42 24 E7 59 35 Ainsi, deux facteurs contribuent à la baisse du niveau d'aisance ; en l'occurrence, il s'agit de la mention du recours à une procédure d'exception ou la demande du médecin de faire signer le formulaire par le pharmacien à sa place. De façon générale, les cliniciens détestent les mesures administratives de contraintes visant à justifier leur conduite clinique [18,19]. De plus, le recours à des ressources non-médicales lors de ces procédures n'offre pas forcément de meilleure issue [20].…”