Impact of a Therapeutic Educational Program on Quality of Life in Alzheimer's Disease: Results of a Pilot Study

Villars, H.; Dupuy, Charlotte; Perrin, Amélie; Vellas, Bruno; Nourhashémi, Fati

doi:10.3233/jad-141179

Cited by 11 publications

(7 citation statements)

References 54 publications

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“…This finding is also in agreement with [18], France, who reported a significant positive effect of a therapeutic educational program on patients' life and that of their caregivers. As well [19], Canada, who indicated that, significant improvement on the posttest participants' attitudes, practices, confidence, and knowledge [14], emphasized that the highest percentage of nurses' knowledge were unsatisfactory and immediately improved after implementation of the guidelines.…”

Section: Discussion Of the Study Findings Are Categorized Under The Fsupporting

confidence: 92%

Training of Formal Caregivers Dealing with Alzheimer Diseased Patients at Helwan City Cairo Egypt

Elkattan¹,

El-Afandy²,

El-Fatah³

2017

AJNS

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Alzheimer prevalence increases with aging and in 2012 it is estimated that Alzheimer worldwide will affect 35.6 million people, this number will double by 2030 and more than triple by 2050. The aim of this study is to evaluate the effect training program for formal caregivers' dealing with Alzheimer diseased patients at Helwan City Cairo Egypt. Design: A quasiexperimental research design was used. Setting: The study was conducted at four available geriatric homes and out-patient psychiatric clinics in Helwan City. Sampling: A purposive sampling was used for selection of forty formal caregivers'. Tool: A self-designed semi-structured interview questionnaire was used, it included demographic information as; age, sex, professional qualification, and experience, formal caregiver's knowledge regarding Alzheimer disease as definition of Alzheimer, causes, risk factor, prevention and control, attitude questionnaire as I feel confident about people with Alzheimer disease, and I feel uncomfortable being around Alzheimer diseased people and related dementia, and formal caregiver's practices as Practice methods of non-therapeutic care to deal with Alzheimer patients, and Configure appropriate environment to Alzheimer patients Results: The pre /posttests among formal caregivers revealed that overall knowledge, attitude and practices improved with highly statistically significant differences at p <0.001 that approved the hypothesis of implementing training program for formal caregivers. Conclusion: The training program significantly brought out improvements in formal caregivers knowledge, attitude and practices regarding Alzheimer diseased patients. Recommendations: The study can be replicated with a larger number of formal caregivers for generalizations of the results, and further studies conduct to improve nurse's knowledge and practices regarding caring for Alzheimer diseased patients.

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Section: Discussion Of the Study Findings Are Categorized Under The Fsupporting

confidence: 92%

Training of Formal Caregivers Dealing with Alzheimer Diseased Patients at Helwan City Cairo Egypt

Elkattan¹,

El-Afandy²,

El-Fatah³

2017

AJNS

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“…Physical exercise reduced neuropsychiatric symptoms in patients with mild dementia [64]. A program of therapeutic education for patients and caregivers improve the quality of life [65]. Finally, multicomponent programs have been shown to improve apathy, anxiety, depression, and quality of life [66].…”

Section: Discussionmentioning

confidence: 99%

Self-Perceived Quality of Life Among Patients with Alzheimer’s Disease: Two Longitudinal Models of Analysis

Conde-Sala

Turró‐Garriga

Portellano-Ortiz

et al. 2016

JAD

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Abstract.The objective was to analyze the factors that influence self-perceived quality of life (QoL) in patients with Alzheimer's disease (AD), contrasting two different longitudinal models. A total of 127 patients were followed up over 24 months. The instruments applied were: Quality of Life in Alzheimer's Disease scale (QoL-AD), Geriatric Depression Scale-15, Anosognosia Questionnaire-Dementia, Disability Assessment in Dementia, Neuropsychiatric Inventory, and the Mini-Mental State Examination. Two models for grouping patients were tested: 1) Baseline score on the QoL-AD (QoLBaseline), and 2) Difference in QoL-AD score between baseline and follow-up (QoL-Change). Generalized estimating equations were used to analyze longitudinal data, and multinomial regression analyses were performed. Over the follow-up period the QoL-Baseline model showed greater variability between groups (Wald χ 2 = 172.3, p < 0.001) than did the QoLChange model (Wald χ 2 = 1.7, p = 0.427). In the QoL-Baseline model the predictive factors were greater depression (odds ratio [OR] = 1.20; 95% CI: 1.00-1.45) and lower functional ability (OR = 0.92; 95% CI: 0.85-0.99) for the Low QoL group (< 33 QoL-AD), and less depression (OR = 0.68; 95% CI: 0.52-0.88), more anosognosia (OR = 1.07; 95% CI: 1.01-1.13), and fewer neuropsychiatric symptoms (OR = 0.95; 95% CI: 0.91-0.99) for the High-QoL group (>37 QoL-AD). The model based on baseline scores (QoL-Baseline) was better than the QoL-Change model in terms of identifying trajectories and predictors of QoL in AD.

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“…We conducted a sample size estimation based on the existing literature [ 31 , 32 ] and a pilot study we previously carried out [ 33 ]. The size was initially 170 dyads; however, during data monitoring, an unexpected 11% of unexploitable data for the primary outcome led us to include 26 additional dyads.…”

Section: Methodsmentioning

confidence: 99%

Impact of an educational programme on Alzheimer’s disease patients’ quality of life: results of the randomized controlled trial THERAD

et al. 2021

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Background Although educational interventions are recommended in Alzheimer’s disease (AD), studies assessing the impact of interventions such as “therapeutic patient education” are scarce. Indeed, the intrinsic nature of the disease is considered a barrier to patients’ involvement in such approaches. We aimed to evaluate an intervention by using a “dyadic” approach (patient and caregiver) in both intervention and assessment. Methods THERAD is a monocentric, randomized, controlled trial assessing the effects of a 2-month educational programme in mild to moderately severe AD patients among 98 dyads (caregiver/patient) on caregiver-reported patient quality of life (QOL) at 2 months. Community-dwelling patients and their caregivers were recruited in ambulatory units of the French Toulouse University Hospital. Self-reported patient QOL, autonomy, behavioural and psychological symptoms and caregiver QOL and burden were collected at 2, 6 and 12 months. Linear mixed models were used in modified intention-to-treat populations. We also performed sensitivity analysis. Results A total of 196 dyads were included, 98 in each group. The mean age of the patients was 82 years, 67.7% were women, diagnosed with AD (+/- cerebrovascular component) (mean MMSE =17.6), and 56.9% lived with a partner. The mean age of the caregivers was 65.7 years, and 64.6% were women (52.3% offspring/42.6% spouses), with a moderate burden (mean Zarit score = 30.9). The mean caregiver-reported patient QOL was lower than the self-reported QOL (28.61 vs. 33.96). We did not identify any significant difference in caregiver-reported patients’ QOL (p = 0.297) at 2 months, but there was a significant difference in self-reported patients’ QOL at 2 months (p = 0.0483) or 6 months (p = 0.0154). No significant difference was found for the secondary outcomes. The results were stable in the sensitivity analyses. Conclusions This randomized controlled trial assessing an educational intervention in 196 dyads (Alzheimer’s disease affected patient/caregiver) highlights the need to better consider the patient’s point of view, since only the self-reported QOL was improved. Additional studies using this dyadic approach are necessary in targeted subpopulations of caregivers (spouse vs. child, gender) and of patients (severity of cognitive impairment or behavioural disturbances) Trial registration THERAD study NCT01796314. Registered on February 19, 2013.

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Impact of a Therapeutic Educational Program on Quality of Life in Alzheimer's Disease: Results of a Pilot Study

Cited by 11 publications

References 54 publications

Training of Formal Caregivers Dealing with Alzheimer Diseased Patients at Helwan City Cairo Egypt

Training of Formal Caregivers Dealing with Alzheimer Diseased Patients at Helwan City Cairo Egypt

Self-Perceived Quality of Life Among Patients with Alzheimer’s Disease: Two Longitudinal Models of Analysis

Impact of an educational programme on Alzheimer’s disease patients’ quality of life: results of the randomized controlled trial THERAD

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