Impact of a New Motion-Correction Algorithm on Image Quality of Low-Dose Coronary CT Angiography in Patients with Insufficient Heart Rate Control

Fuchs, Tobias A.; Stehli, Julia; Dougoud, Svetlana; Fiechter, Michael; Sah, Bert-Ram; Buechel, Ronny R.; Bull, Sacha; Gaemperli, Oliver; Kaufmann, Philipp A.

doi:10.1016/j.acra.2013.10.014

Cited by 44 publications

(33 citation statements)

References 26 publications

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“…In recent years, motion correction technology has advanced substantially, including the introduction of SnapShot Freeze™ (GE Healthcare, Waukesha, WI -SSF) -an approach that estimates and corrects for motion of the coronary arteries. The improvements in image quality due to SSF have been shown in many studies to improve diagnostic accuracy and image interpretability [2][3][4][5][6][7][8][9][10], and results from the ongoing multi-center ViCTORY trial [11] are expected shortly. However, SSF was initially designed primarily for correcting artifacts near the coronary arteries, not for correcting motion artifacts in the myocardium.…”

Section: Introductionmentioning

confidence: 96%

Motion correction for improving the accuracy of dual-energy myocardial perfusion CT imaging

et al. 2016

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Coronary Artery Disease (CAD) is the leading cause of death globally [1]. Modern cardiac computed tomography angiography (CCTA) is highly effective at identifying and assessing coronary blockages associated with CAD. The diagnostic value of this anatomical information can be substantially increased in combination with a non-invasive, lowdose, correlative, quantitative measure of blood supply to the myocardium. While CT perfusion has shown promise of providing such indications of ischemia, artifacts due to motion, beam hardening, and other factors confound clinical findings and can limit quantitative accuracy. In this paper, we investigate the impact of applying a novel motion correction algorithm to correct for motion in the myocardium. This motion compensation algorithm (originally designed to correct for the motion of the coronary arteries in order to improve CCTA images) has been shown to provide substantial improvements in both overall image quality and diagnostic accuracy of CCTA. We have adapted this technique for application beyond the coronary arteries and present an assessment of its impact on image quality and quantitative accuracy within the context of dual-energy CT perfusion imaging. We conclude that motion correction is a promising technique that can help foster the routine clinical use of dual-energy CT perfusion. When combined, the anatomical information of CCTA and the hemodynamic information from dual-energy CT perfusion should facilitate better clinical decisions about which patients would benefit from treatments such as stent placement, drug therapy, or surgery and help other patients avoid the risks and costs associated with unnecessary, invasive, diagnostic coronary angiography procedures.

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Section: Introductionmentioning

confidence: 96%

Motion correction for improving the accuracy of dual-energy myocardial perfusion CT imaging

et al. 2016

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“…In addition, 4-dimensional CT or volumetric cine imaging is possible if the X-ray beam is turned on for a longer period to capture the heart over one or more cardiac cycles [7]. Other proposed methods to overcome motion-induced image degradation include an opening of the padding (adding surrounding X-ray beam time to the mid-diastolic window with retrospective gating), multi-segmental reconstruction and motion correction algorithm [8–10]. Padding with retrospective gating and multi-segmental reconstruction are associated with substantial increase of patient dose.…”

Section: Introductionmentioning

confidence: 99%

“…Padding with retrospective gating and multi-segmental reconstruction are associated with substantial increase of patient dose. Fuchs et al [8] have reported image quality improvement and interpretability of prospectively ECG-triggered CCTA with motion correction algorithm at average heart rate of 69 ± 9 beats per minute (bpm).…”

Section: Introductionmentioning

confidence: 99%

Recent Update on Radiation Dose Assessment for the State-of-the-Art Coronary Computed Tomography Angiography Protocols

Tan

Yeong

et al. 2016

PLoS ONE

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ObjectivesThis study aimed to measure the absorbed doses in selected organs for prospectively ECG-triggered coronary computed tomography angiography (CCTA) using five different generations CT scanners in a female adult anthropomorphic phantom and to estimate the effective dose (HE).Materials and MethodsProspectively ECG-triggered CCTA was performed using five commercially available CT scanners: 64-detector-row single source CT (SSCT), 2 × 32-detector-row-dual source CT (DSCT), 2 × 64-detector-row DSCT and 320-detector-row SSCT scanners. Absorbed doses were measured in 34 organs using pre-calibrated optically stimulated luminescence dosimeters (OSLDs) placed inside a standard female adult anthropomorphic phantom. HE was calculated from the measured organ doses and compared to the HE derived from the air kerma-length product (PKL) using the conversion coefficient of 0.014 mSv∙mGy-1∙cm-1 for the chest region.ResultsBoth breasts and lungs received the highest radiation dose during CCTA examination. The highest HE was received from 2 × 32-detector-row DSCT scanner (6.06 ± 0.72 mSv), followed by 64-detector-row SSCT (5.60 ± 0.68 and 5.02 ± 0.73 mSv), 2 × 64-detector-row DSCT (1.88 ± 0.25 mSv) and 320-detector-row SSCT (1.34 ± 0.48 mSv) scanners. HE calculated from the measured organ doses were about 38 to 53% higher than the HE derived from the PKL-to-HE conversion factor.ConclusionThe radiation doses received from a prospectively ECG-triggered CCTA are relatively small and are depending on the scanner technology and imaging protocols. HE as low as 1.34 and 1.88 mSv can be achieved in prospectively ECG-triggered CCTA using 320-detector-row SSCT and 2 × 64-detector-row DSCT scanners.

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“…12,13 Furthermore, algorithms that correct for motion during reconstruction are becoming clinically available. 14,15 Even when using these techniques, it is still prudent to avoid as much motion during acquisition as possible. Thus, the results and methods presented in this work can supplement advanced reconstruction techniques.…”

Section: Discussionmentioning

confidence: 99%

Characterization of cardiac quiescence from retrospective cardiac computed tomography using a correlation‐based phase‐to‐phase deviation measure

et al. 2015

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Purpose: Accurate knowledge of cardiac quiescence is crucial to the performance of many cardiac imaging modalities, including computed tomography coronary angiography (CTCA). To accurately quantify quiescence, a method for detecting the quiescent periods of the heart from retrospective cardiac computed tomography (CT) using a correlation-based, phase-to-phase deviation measure was developed. Methods: Retrospective cardiac CT data were obtained from 20 patients (11 male, 9 female, 33-74 yr) and the left main, left anterior descending, left circumflex, right coronary artery (RCA), and interventricular septum (IVS) were segmented for each phase using a semiautomated technique. Cardiac motion of individual coronary vessels as well as the IVS was calculated using phase-to-phase deviation. As an easily identifiable feature, the IVS was analyzed to assess how well it predicts vessel quiescence. Finally, the diagnostic quality of the reconstructed volumes from the quiescent phases determined using the deviation measure from the vessels in aggregate and the IVS was compared to that from quiescent phases calculated by the CT scanner. Three board-certified radiologists, fellowship-trained in cardiothoracic imaging, graded the diagnostic quality of the reconstructions using a Likert response format: 1 = excellent, 2 = good, 3 = adequate, 4 = nondiagnostic. Results: Systolic and diastolic quiescent periods were identified for each subject from the vessel motion calculated using the phase-to-phase deviation measure. The motion of the IVS was found to be similar to the aggregate vessel (AGG) motion. The diagnostic quality of the coronary vessels for the quiescent phases calculated from the aggregate vessel (P AGG ) and IVS (P IVS ) deviation signal using the proposed methods was comparable to the quiescent phases calculated by the CT scanner (P CT ). The one exception was the RCA, which improved for P AGG for 18 of the 20 subjects when compared to P CT (P CT = 2.48; P AGG = 2.07, p = 0.001). Conclusions: A method for quantifying the motion of specific coronary vessels using a correlationbased, phase-to-phase deviation measure was developed and tested on 20 patients receiving cardiac CT exams. The IVS was found to be a suitable predictor of vessel quiescence. The diagnostic quality of the quiescent phases detected by the proposed methods was comparable to those calculated by the CT scanner. The ability to quantify coronary vessel quiescence from the motion of the IVS can be used to develop new CTCA gating techniques and quantify the resulting potential improvement in CTCA image quality. C 2015 American Association of Physicists in Medicine.

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Impact of a New Motion-Correction Algorithm on Image Quality of Low-Dose Coronary CT Angiography in Patients with Insufficient Heart Rate Control

Cited by 44 publications

References 26 publications

Motion correction for improving the accuracy of dual-energy myocardial perfusion CT imaging

Motion correction for improving the accuracy of dual-energy myocardial perfusion CT imaging

Recent Update on Radiation Dose Assessment for the State-of-the-Art Coronary Computed Tomography Angiography Protocols

Characterization of cardiac quiescence from retrospective cardiac computed tomography using a correlation‐based phase‐to‐phase deviation measure

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