Impact of 24-month fluoride tablet program on children with disabilities in a non-fluoridated country

Liu, Hsiu-Yueh; Hung, Hsin-Chia; Hsiao, Szu‐Yu; Chen, Hong-Sen; Yen, Yea‐Yin; Huang, Shun‐Te; Chen, Chun-Chih; Chen, Ping-Ho; Chen, Cheng-Chin; Lin, Pei‐Chen; Lu, Ye-Hsu

doi:10.1016/j.ridd.2013.05.006

Cited by 8 publications

(24 citation statements)

References 24 publications

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“…; Liu et al . ). Three studies measured the caries experience by decayed, missing, and filled due to caries indices at tooth and surface level (Luoma et al .…”

Section: Resultsmentioning

confidence: 97%

“…; Liu et al . ). Another trial indicated that powered toothbrush plus calcium sucrose phosphate dentifrices would be ‘a better alternative’ to low fluoride toothpaste (Awasthi et al .…”

Section: Resultsmentioning

confidence: 97%

“…; Liu et al . ). The fixed‐effect model showed that fluoride was more effective in caries prevention than the controls [ Z = 2.02, P = 0.04, 95% CI: −0.71 (−1.40, −0.02)] (Fig.…”

Section: Resultsmentioning

confidence: 97%

“…Eight studies did not specify the ID levels of their study population, but the authors had mentioned that their target population were intellectually disabled (Liu et al . ), mentally handicapped (Luoma et al . ), mentally retarded (Russell & Bay ; Andrade Meyer et al .…”

Section: Resultsmentioning

confidence: 99%

“…Caregivers and parents of the disabled children have expressed concerns regarding the physical condition of their children and the safety of fluoride (Liu et al . ). One effective approach to reduce the side effects of fluoride is to control the amount of fluoridated toothpaste.…”

Section: Discussionmentioning

confidence: 97%

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Efficacy of caries and gingivitis prevention strategies among children and adolescents with intellectual disabilities: a systematic review and meta‐analysis

Zhou

Wong

Wen

et al. 2018

J intellect Disabil Res

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Background Dental caries and periodontal diseases are the most common oral diseases among human beings. Individuals with intellectual disabilities (IDs) have poor oral health and limited access to dental care. The aim of this study was to investigate the efficacy of strategies in caries and gingivitis prevention among children and adolescents with ID. Methods Four electronic databases (PubMed, Cochrane Library, Web of Science and Scopus) were searched from their commencement date to 17 April 2017. Randomised or non-randomised controlled trials evaluating the efficacy of interventions in caries and gingivitis prevention were included if the participants were children and adolescents with ID. Gingival index and caries experiences were reported in the format of mean difference and standard error. Metaanalysis was conducted if data could be pooled from two or more studies using similar outcome measurements and intervention. Results A total of 1455 articles published in English were identified. Fourteen studies formed the basis of qualitative analysis; six studies were feasible to perform quantitative analysis. Meta-analysis favoured fluoride to placebo in caries prevention [Z = 2.02, P < 0.05, 95% CI: À0.71 (À1.40, À0.02)], while the effectiveness of chlorhexidine remained elusive. Conclusions Both mechanical and chemical approaches had been applied to caries and gingivitis prevention among children and adolescents with ID. Insufficient evidence supported the efficacy of chlorhexidine nor powered toothbrush, while fluoride was suggested to be an effective caries preventive strategy in fluoride-deficient areas. More welldesigned randomised controlled trials using integration strategies are encouraged in further studies.(1) = (2) CHX (spray, 0.12%) = placebo CHX, chlorhexidine; CT, controlled trial; RCT, randomised controlled trial.

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“…; Liu et al . ). Three studies measured the caries experience by decayed, missing, and filled due to caries indices at tooth and surface level (Luoma et al .…”

Section: Resultsmentioning

confidence: 97%

“…; Liu et al . ). Another trial indicated that powered toothbrush plus calcium sucrose phosphate dentifrices would be ‘a better alternative’ to low fluoride toothpaste (Awasthi et al .…”

Section: Resultsmentioning

confidence: 97%

“…; Liu et al . ). The fixed‐effect model showed that fluoride was more effective in caries prevention than the controls [ Z = 2.02, P = 0.04, 95% CI: −0.71 (−1.40, −0.02)] (Fig.…”

Section: Resultsmentioning

confidence: 97%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 97%

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Efficacy of caries and gingivitis prevention strategies among children and adolescents with intellectual disabilities: a systematic review and meta‐analysis

Zhou

Wong

Wen

et al. 2018

J intellect Disabil Res

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Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years

Chou,

Bougatsos,

Griffin

et al. 2023

JAMA

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ImportanceDental caries is common in children and adolescents aged 5 to 17 years and potentially amenable to primary care screening and prevention.ObjectiveTo systematically review the evidence on primary care screening and prevention of dental caries in children and adolescents aged 5 to 17 years to inform the US Preventive Services Task Force.Data SourcesMEDLINE, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews (to October 3, 2022); surveillance through July 21, 2023.Study SelectionDiagnostic accuracy of primary care screening instruments and oral examination; randomized and nonrandomized trials of screening and preventive interventions and systematic reviews of such studies; cohort studies on primary care oral health screening and preventive intervention harms.Data Extraction and SynthesisOne investigator abstracted data; a second checked accuracy. Two investigators independently rated study quality. Random-effects meta-analysis was performed for fluoride supplements and xylitol; for other preventive interventions, pooled estimates were used from good-quality systematic reviews.Main Outcomes and MeasuresDental caries, morbidity, functional status, quality of life, harms; diagnostic test accuracy.ResultsThree systematic reviews (total 20 684 participants) and 19 randomized clinical trials, 3 nonrandomized trials, and 1 observational study (total 15 026 participants) were included. No study compared screening vs no screening. When administered by dental professionals or in school settings, fluoride supplements compared with placebo or no intervention were associated with decreased change from baseline in the number of decayed, missing, or filled permanent teeth (DMFT index) or decayed or filled permanent teeth (DFT index) (mean difference, −0.73 [95% CI, −1.30 to −0.19]) at 1.5 to 3 years (6 trials; n = 1395). Fluoride gels were associated with a DMFT- or DFT-prevented fraction of 0.18 (95% CI, 0.09-0.27) at outcomes closest to 3 years (4 trials; n = 1525), fluoride varnish was associated with a DMFT- or DFT-prevented fraction of 0.44 (95% CI, 0.11-0.76) at 1 to 4.5 years (5 trials; n = 3902), and resin-based sealants were associated with decreased risk of carious first molars (odds ratio, 0.21 [95% CI, 0.16-0.28]) at 48 to 54 months (4 trials; n = 440). No trial evaluated primary care counseling or dental referral. Evidence on screening accuracy, silver diamine fluoride, xylitol, and harms was very limited, although serious harms were not reported.Conclusions and RelevanceAdministration of fluoride supplements, fluoride gels, varnish, and sealants in dental or school settings improved caries outcomes. Research is needed on the effectiveness of oral health preventive interventions in primary care settings and to determine the benefits and harms of screening.

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Screening and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years

Barry,

Nicholson,

Silverstein

et al. 2023

JAMA

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ImportanceOral health is fundamental to health and well-being across the lifespan. Oral health conditions affect the daily lives of school-age children and adolescents, leading to loss of more than 51 million school hours every year. Untreated oral health conditions in children can lead to serious infections and affect growth, development, and quality of life.ObjectiveThe US Preventive Services Task Force (USPSTF) commissioned a systematic review to evaluate screening and preventive interventions for oral health conditions in children and adolescents aged 5 to 17 years.PopulationAsymptomatic children and adolescents aged 5 to 17 years.Evidence AssessmentThe USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for oral health conditions (eg, dental caries) performed by primary care clinicians in asymptomatic children and adolescents aged 5 to 17 years. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of preventive interventions for oral health conditions (eg, dental caries) performed by primary care clinicians in asymptomatic children and adolescents aged 5 to 17 years.RecommendationsThe USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of routine screening performed by primary care clinicians for oral health conditions, including dental caries, in children and adolescents aged 5 to 17 years. (I statement) The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of preventive interventions performed by primary care clinicians for oral health conditions, including dental caries, in children and adolescents aged 5 to 17 years. (I statement)

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Impact of 24-month fluoride tablet program on children with disabilities in a non-fluoridated country

Cited by 8 publications

References 24 publications

Efficacy of caries and gingivitis prevention strategies among children and adolescents with intellectual disabilities: a systematic review and meta‐analysis

Efficacy of caries and gingivitis prevention strategies among children and adolescents with intellectual disabilities: a systematic review and meta‐analysis

Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years

Screening and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years

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