Impact de l’annuloplastie mitrale combinée à la revascularisation chirurgicale dans l’insuffisance mitrale ischémique

Tribak, M.; Konaté, Madiassa; hbib, B. Ould; Perel, Konan; Mahfoudi, Loubna; Hassani, Anne; Daouda, A.; Lachhab, Fadoua; Bendagha, N.; Soufiani, Aida; Fila, J.; Maghraoui, Souad; Bensouda, A.; Marmade, L.; Moughil, S.

doi:10.1016/j.ancard.2017.04.013

Cited by 1 publication

(1 citation statement)

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“…The cardiopulmonary bypass was claimed to activate a defensive response to its components and non-physiological blood flow created by roller pumps [27,28]. The concomitant valve pathology requiring surgical interventions was excluded since combined procedures carry increased mortality risk [29,30].…”

Section: Discussionmentioning

confidence: 99%

The Significance of Systemic Immune-Inflammatory Index for Mortality Prediction in Diabetic Patients Treated with Off-Pump Coronary Artery Bypass Surgery

et al. 2022

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Diabetes mellitus (DM) represents a complex carbohydrate metabolism disorder characterized by inflammatory over-reactivity. The study aimed to investigate the potential influence of postoperative inflammatory activation on mortality risk after off-pump coronary artery bypass grafting in diabetic patients. There were 510 patients treated with off-pump coronary artery bypass grafting due to stable complex coronary artery disease, including 175 patients with type-2 DM (T2DM.) The mean follow-up time was 3.7 +/− 1.5 years with a 9% all-cause mortality rate in the diabetic group. In multivariable analysis, preoperative comorbidities (stroke, peripheral artery disease, postoperative systemic inflammatory index >952, and postoperative left ventricle ejection fraction (LVEF) < 45%) were revealed as prognostic factors. The receiver operator characteristics curve analysis for postoperative calculations of systemic immune-inflammatory index (SII) appeared significant (AUC = 0.698, p = 0.008), yielding sensitivity of 68.75% and specificity of 71.07%. Systemic immune-inflammatory index (SII) can be regarded as a predictive marker for long-term prognosis in diabetic patients after off-pump coronary artery bypass grafting. The role of perioperative inflammatory activation may play a crucial role in mortality prediction.

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