Impact and Evolution of Peliosis Hepatis in Renal Transplant Recipients

Cavalcanti, Ruy; Pol, Stanislas; Carnot, Françoise; Campos, Henry de Holanda; Degott, Claude; Driss, Françoise; Legendre, Christophe; Kreis, Henri

doi:10.1097/00007890-199408000-00011

Cited by 49 publications

(28 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Occasionally, this condition may occur in the spleen and the bone marrow. Peliosis has mostly been reported in adult patients associated with chronic infections such as HIV [10] or the use of specific drugs [6,7,11] . In many cases, removal of the causative agent had caused regression of the disease [12] .…”

Section: Discussionmentioning

confidence: 99%

“…PH has also been reported after prolonged use of anabolic steroids (e.g. azathioprine [6] , 6-thioguanine, and 6-mercaptopurine [7] ) and oral contraceptives [8] . PH varies from minimal asymptomatic lesions to larger massive lesions that may present with cholestasis, liver failure, portal hypertension, avascular mass lesion, or even spontaneous rupture [9] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Spontaneous liver rupture in a patient with peliosis hepatis:A case report

Choi¹,

Jin²,

Cho³

et al. 2009

WJG

View full text Add to dashboard Cite

Peliosis hepatis is a rare pathological entity and may cause fatal hepatic hemorrhage and liver failure. Here, we present a young male patient with aplastic anemia, who had received long-term treatment with oxymetholone. The patient suffered from sudden onset of intra-abdominal hemorrhage with profuse hemoperitoneum. The patient was treated successfully with a right hemihepatectomy and is in good health after 13 postoperative months. We suggest that peliosis hepatis be considered in patients with hepatic parenchymal hematoma, especially in patients under prolonged synthetic anabolic steroid medication. The possibility of a potentially life-threatening complication of massive intra-abdominal bleeding should also be considered.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Spontaneous liver rupture in a patient with peliosis hepatis:A case report

Choi¹,

Jin²,

Cho³

et al. 2009

WJG

View full text Add to dashboard Cite

show abstract

“…It is mostly seen in adult patients in association with diseases such as acquired immunodeficiency syndrome, malnutrition, tuberculosis, leprosy, vasculitis, hematological neoplasms, hepatocellular adenoma and carcinoma, androgenic anabolic steroids and estrogens, immunosuppressive drugs, tamoxifene, toxic substances (arsenic, vinyl chloride), infections (Bartonella henselae) and in renal transplant recipients receiving immunosuppressive treatment. [4,5] The pathophysiology of PH is still largely speculative. It has been attributed to an increased sinusoidal pressure because of difficulties in blood outflow from the liver, leading to parenchymal necrosis of liver cells and sinusoidal wall weakness.…”

Section: Case Reportmentioning

confidence: 99%

“…There are diverse etiologies of this condition; however, the cause remains unclear in 25-50% of patients. [1][2][3][4][5] The pathogenesis and management are still controversial. Prognosis is largely determined by the underlying cause and is generally guarded.…”

Section: Introductionmentioning

confidence: 99%

Peliosis hepatis complicating pregnancy: A rare entity

Butt

Luck

Hassan

et al. 2017

Journal of Translational Internal Medicine

View full text Add to dashboard Cite

Peliosis hepatis (PH) is a rare, benign condition of the liver characterized by the presence of blood-filled lacunar spaces in the parenchyma. It usually has a chronic presentation and is a rare cause of portal hypertension reported in adult patients. Its etiology is diverse and ranges from infectious agents to tumors to toxic substances and anabolic steroids; however, the cause remains unclear in 25-50% of patients. Similarly, the symptomatology and imaging findings are diverse. Biopsy is the definitive test to diagnose the condition. Herein, we present a case of a young female presenting in her seventh month of gestational amenorrhea with signs of portal hypertension and subsequently diagnosed to have PH. She was managed conservatively and delivered her baby normally. Later, she presented with spontaneous bacterial peritonitis and hepatic encephalopathy and developed hepatorenal syndrome. She later succumbed to her illness. The condition should be kept in the differential diagnosis of the atypical liver masses and liver diseases causing portal hypertension.

show abstract

“…In rare cases, it may cause liver failure, cholestasis, portal hypertension, or spontaneous rupture of the liver. Fatal cases have been described, which are frequently associated with congenital disease, but spontaneous arrest of the hemorrhage has also been reported [14,15].…”

Section: Peliosis Hepatismentioning

confidence: 99%

Acute nontraumatic liver lesions

Caremani¹,

Tacconi²,

Lapini³

2013

J Ultrasound

View full text Add to dashboard Cite

The principal conditions requiring emergency/ urgent intervention in patients with nontraumatic liver lesions are hemorrhage (with or without tumor rupture), rupture of hydatid cysts (with or without infection), complications arising from liver abscesses or congenital liver cysts, rupture related to peliosis hepatis, and in rare cases spontaneous hemorrhage. This article examines each of these conditions, its appearance on ultrasound (the first-line imaging method of choice for assessing any urgent nontraumatic liver lesion) and indications for additional imaging studies.Keywords Acute liver disorders Á Ultrasound Á Contrast-enhanced ultrasound Sommario Le principali cause di emergenza/urgenza in patologia epatica non traumatica sono l'emorragia con o senza rottura di neoplasie epatiche, la rottura con o senza infezione delle cisti idatidee, le complicanze degli ascessi epatici, delle cisti congenite del fegato, l'emorragia, la rottura in corso di peliosi epatica e la rara emorragia spontanea. Dopo aver esaminato singolarmente le varie cause di emergenza/urgenza, i rispettivi aspetti ecografici e l'integrazione con altre metodiche di imaging si conclude che nei pazienti con patologia epatica l'ecografia, con o senza mezzo di contrasto, è la metodica da utilizzare in prima istanza ad ogni emergenza/urgenza non traumatica del fegato.

show abstract

Impact and Evolution of Peliosis Hepatis in Renal Transplant Recipients

Cited by 49 publications

References 0 publications

Spontaneous liver rupture in a patient with peliosis hepatis:A case report

Spontaneous liver rupture in a patient with peliosis hepatis:A case report

Peliosis hepatis complicating pregnancy: A rare entity

Acute nontraumatic liver lesions

Contact Info

Product

Resources

About