Impact and clinical significance of recurrent venous thromboembolism

Labropoulos, Nicos; Spentzouris, Georgios; Gasparis, Antonios P.; Meissner, Mark H.

doi:10.1002/bjs.7156

Cited by 18 publications

(21 citation statements)

References 78 publications

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“…This is why diagnosis of recurrent VTE should be based on objective assessments (for review see Labropoulos et al [27]). As regards the workup for diagnosis/exclusion of suspected recurrent DVT, Prandoni et al proposed a simple ultrasound method for measuring thrombus regression in patients with previous proximal DVT; the vein diameter under maximum compression (thrombus thickness) is measured in the involved venous segment and a noncompressibility of a previous normal(ized) venous segment or an increase of the residual diameter of ≥2 mm is considered diagnostic of recurrent proximal DVT [28].…”

Section: Diagnosis Of Recurrences and How They Usually Presentmentioning

confidence: 99%

Recurrent Venous Thromboembolism: What Is the Risk and How to Prevent It

Palareti¹

2012

Scientifica

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Venous thromboembolism (VTE) that includes deep vein thrombosis and/or pulmonary embolism is a frequent, severe, and potentially lethal disease. After a first episode, VTE has a strong tendency to recur. While VTE is an acute disease, it may have variable outcomes in early and late phases after initial presentation. Furthermore, the incidence of late, clinically important consequences (postthrombotic syndrome and/or chronic thromboembolic pulmonary hypertension) increases in case of recurrent events. The aims of the present review are (i) to analyze the incidence and risk factors for recurrence of VTE (either those related to the type of first thrombotic event or to the patients), the risks associated with occurrence of recurrent events, and the problems linked to the diagnosis, not always easy, of recurrent events; (ii) to discuss whether or not it is possible to predict the individual risk of recurrence after a first event, by stratifying patients at high or low risk of recurrence, and how this can influence their treatment; (iii) to comment what the current guidelines and guidance suggest/recommend about anticoagulant treatment after a first VTE event and, finally, to propose practical indications on how to manage individual patients affected by VTE.

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Section: Diagnosis Of Recurrences and How They Usually Presentmentioning

confidence: 99%

Recurrent Venous Thromboembolism: What Is the Risk and How to Prevent It

Palareti¹

2012

Scientifica

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“…[8][9][10][11] Patients with multiple VTE events are at increased risk for serious VTE-related chronic complications including pulmonary hypertension and postthrombotic syndrome. 12,13 The treatment of episodes of recurrent DVT has been estimated to cost 21% more than treatment for the initial event. 14 Previously published VTE cost estimates have focused either on initial VTE events only or on aggregate follow-up costs (i.e., the combined costs of initial and recurrent events).…”

mentioning

confidence: 99%

Economic burden of recurrent venous thromboembolism: Analysis from a U.S. hospital perspective

Casciano¹,

Dotiwala²,

Kemp

et al. 2015

American Journal of Health-System Pharmacy

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“…The risk factors for developing DVT include recent surgery and hormonal contraceptive therapy; DVT is also more common in women. These risk factors increase the likelihood of clot formation in the pelvis and lower limbs, which can eventually cause PE [5] .…”

Section: Discussionmentioning

confidence: 99%

“…Tests such as D-dimer, venous Doppler of lower limbs, and chest CTs are useful for the study of DVT and PE [5] , but when stroke is concurrent, brain CT and echocardiogram are mandatory [2] . In our patient, D-dimer was not performed because the initial symptoms were dyspnea and dysarthria.…”

Section: Discussionmentioning

confidence: 99%

Surgical Treatment for Thrombus Straddling a Patent Foramen Ovale

Oliveira¹,

Sabbag²,

Brandi³

et al. 2016

Brazilian Journal of Cardiovascular Surgery

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We present a case of a 41-year-old female with deep vein thrombosis after abdominal surgery. The patient quickly developed severe pulmonary embolism and stroke representative of paradoxical embolism. Echocardiography showed a thrombus straddling a patent foramen ovale, which was confirmed intraoperatively. An accurate diagnosis and rapid treatment decisions are crucial for preventing patient deterioration in the form of new pulmonary embolisms or stroke.

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Impact and clinical significance of recurrent venous thromboembolism

Abstract: The role and weight of the predictive factors for recurrent VTE and its sequelae, and the type and optimal duration of anticoagulation have not been studied adequately. Fatality associated with pulmonary embolism and rates of recurrent VTE remain unacceptably high.

Cited by 18 publications

References 78 publications

Recurrent Venous Thromboembolism: What Is the Risk and How to Prevent It

Recurrent Venous Thromboembolism: What Is the Risk and How to Prevent It

Economic burden of recurrent venous thromboembolism: Analysis from a U.S. hospital perspective

Surgical Treatment for Thrombus Straddling a Patent Foramen Ovale

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