Immuotactoid Glomerulopathy (Fibrillary Glomerulonephritis)

The Spectrum of Kidney Involvement in Lymphoma: A Case Report and Review of the Literature

“…ITG has been associated with lymphoproliferative disorders in up to 33% of cases in one series 24 , although when paraproteinemia and monoclonal gammopathy were excluded, the prevalence fell to ≤7%. Prognosis is poor, with over 50% developing end-stage kidney disease by five years 25 .…”

Glomerulopathy with fibrillary and tubular deposits

“…1) отложения хаотично расположенных, неразветвленных, внешне оди-наковых фибрилл диаметром от 12 до 24 нм (наиболее ча-сто 18-22 нм) [1,16,18,19]. Следует отметить, что раз-меры фибрилл зависят от способа заливки материала при электронно-микроскопическом исследовании [17,20].…”

“…S. Korbet и соавт. [19] опубликовали электронно-микроскопические фотографии амилоида при увеличении в 250 000 раз, на которых четко показана тубулярная структура амилоидных фибрилл. Толщина амилоидных тубулярных структур обычно менее 12 нм, чаще всего 8-10 нм.…”

Monoclonal gammopathy and glomerulopathy associated with chronic lymphocytic leukemia

“…On the other hand, ITG causes progressive renal failure, with more than 50% of patients progressing to endstage renal disease over 2-5 years. 2 The patient presented was quite young and, from a renal perspective, was in a poor prognostic group as he was nephrotic and had rapidly progressive renal failure. His physicians decided to use a 'conventional' immunosuppression regimen that is often efficacious in focal necrotizing glomerulonephritis, namely cyclophosphamide and prednisone.…”