Immunotoxicological Threats of Pollutants in Aquatic Invertebrates

Ray, Sajal; Mukherjee, Soumalya; Bhunia, Niladri Sekhar; Bhunia, AnindyaSundar; Ray, Mitali

doi:10.5772/60216

Cited by 9 publications

(4 citation statements)

References 22 publications

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“…The field of immunotoxicology in wildlife is relatively new, and there is scarce knowledge about this subject in reptiles (Siroski et al, 2016). Nevertheless, it has been reported that some pesticides affects defense mechanisms and can alter structures of some components of the IS (Ray et al, 2015). Thus, for example, some authors have reported effects of Roundup (RU, glyphosate-based formulation) on some parameters of the IS and growth of Caiman latirostris (Latorre et al, 2013;Siroski et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Effects of cypermethrin (pyrethroid), glyphosate and chlorpyrifos (organophosphorus) on the endocrine and immune system of Salvator merianae (Argentine tegu)

Mestre

Amavet

Vanzetti

et al. 2019

Ecotoxicology and Environmental Safety

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Section: Introductionmentioning

confidence: 99%

Effects of cypermethrin (pyrethroid), glyphosate and chlorpyrifos (organophosphorus) on the endocrine and immune system of Salvator merianae (Argentine tegu)

Mestre

Amavet

Vanzetti

et al. 2019

Ecotoxicology and Environmental Safety

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“…THC adalah total hemosit dalam tubuh gastropoda yang dapat digunakan sebagai biomarker dalam mendeskripsikan suatu status pencemaran lingkungan. Apabila terjadi suatu pencemaran, maka THC akan mengalami kenaikkan [30]. THC terdiri dari sel hyalinosit, semi granulosit, granulosit dan sel-sel yang mati [31].…”

Section: Thc (Total Haemocyte Count)unclassified

HEMOCYTE PROFILE OF SUSUH KURA (Sulcospira Testudinaria) IN ORDER TO EVALUATE THE WATER QUALITY OF BADHER BANK CONSERVATION AREA, TAWANGREJO VILLAGE, BINANGUN DISTRICT, BLITAR

Hertika

Supriatna²,

Darmawan³

et al. 2021

jfmr

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Kawasan Konservasi Badher Bank merupakan kawasan konservasi yang terfokus dalam konservasi Ikan Badher yang merupakan ciri khas di daerah tersebut. Tujuan dari penelitian ini untuk menganalisis profil hemosit Susuh Kura (Sulcospira testudinaria) di Kawasan Konservasi Badher Bank dan menganalisis kualitas air dalam rangka evaluasi kualitas perairan. Metode penelitian yang digunakan adalah deskriptif dengan teknik survei. Sampel yang diambil adalah sampel kualitas air dan susuh kura di 4 stasiun. Berdasakan hasil pengukuran kualitas air didapatkan hasil, suhu berkisar 27,3-30,7°C, kecepatan arus berkisar 0,6-1 m/s, kecerahan berkisar 5-8,7 cm, TSS(Total Suspended Solid) berkisar 11-46 mg/l, pH berkisar 7,31-7,60, DO (Dissolved Oxygen) berkisar 3,6-5,1 mg/l dengan ambang batas minimal 4 mg/l, amoniak berkisar 0,043-0,246 mg/l. Hasil kualitas air, hanya amoniak yang melebihi ambang batas. Hasil pengamatan THC didapatkan nilai antara 28x10 4 -96x10 4 sel/ml. Analisis pada DHC didapatkan hyalinosit berkisar antara 16,28-75,49%, Semi granulosit berkisar antara 3,13-23,53% dan granulosit berkisar antara 8,82-72,09%. Hasil analisis CCA menunjukkan THC, hyalinosit dan semi granulosit dipengaruhi 7 parameter dengan konsentrasi sedang. Sedangkan granulosit cenderung dipengaruhi arus yang tinggi, serta DO dan TSS yang berkonsentrasi sedang sampai tinggi. Berdasarkan analisis yang telah dilakukan, maka dapat disimpulkan kondisi perairan di Kawasan Konservasi Badher Bank masih dalam kondisi normal. Namun, pada stasiun 4 terjadi pencemaran karena adanya masukan air limbah pabrik gula.

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“…Immunotoxicants are environmental contaminants and drugs that disrupt the immune system’s balance and cause damage to living organisms 2 . Common environmental agents that contribute to immune deficiency are stress, some bacterial and fungal toxins, pesticides, alcohol and tobacco abuse, or pharmaceuticals such as antibiotics, chemotherapeutic agents, birth control pills, and neuropsychiatric drugs 3 4 5 .…”

Section: Introductionmentioning

confidence: 99%

Risperidone Toxicity on Human Blood Lymphocytes in Nano molar Concentrations

et al. 2022

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Risperidone is an atypical antipsychotic drug used for the pharmacotherapy of psychiatric disorders. Some reports indicate that risperidone is toxic to various systems of the body, including the immune system. This study evaluated the toxicity effect of risperidone on human blood lymphocytes. To achieve this aim, lymphocytes were isolated using Ficoll paque plus. The results showed that risperidone (12, 24 and 48 nM) causes toxicity in human blood lymphocytes by increasing the level of intracellular reactive oxygen species (ROS), damage to lysosomal membrane, the collapse of the mitochondrial membrane potential (MMP), and increased extracellular oxidized glutathione (GSSG). Also, exposure of human blood lymphocytes to risperidone is associated with a decrease in intracellular glutathione (GSH) levels. Finally, it could be concluded that oxidative stress is one of the mechanisms of risperidone-induced toxicity in human blood lymphocytes.

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Immunotoxicological Threats of Pollutants in Aquatic Invertebrates

Cited by 9 publications

References 22 publications

Effects of cypermethrin (pyrethroid), glyphosate and chlorpyrifos (organophosphorus) on the endocrine and immune system of Salvator merianae (Argentine tegu)

Effects of cypermethrin (pyrethroid), glyphosate and chlorpyrifos (organophosphorus) on the endocrine and immune system of Salvator merianae (Argentine tegu)

HEMOCYTE PROFILE OF SUSUH KURA (Sulcospira Testudinaria) IN ORDER TO EVALUATE THE WATER QUALITY OF BADHER BANK CONSERVATION AREA, TAWANGREJO VILLAGE, BINANGUN DISTRICT, BLITAR

Risperidone Toxicity on Human Blood Lymphocytes in Nano molar Concentrations

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