Abstract:Immunotoxicity can be defined as the adverse effects of toxicants on the immune system. Low‐molecular‐weight chemicals that are able to induce allergy can be divided into contact and respiratory sensitizers. These sensitizers differ not only in their relevant exposure routes and the clinical effects they can induce, but also in risk assessment. Various types of data suggest that the oxidative stress response pathway is the most significant one affected by contact sensitizer exposure. Less abundant, primarily t… Show more
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