Immunotoxicity of copper nanoparticle and copper sulfate in a common Indian earthworm

Gautam, Arunodaya; Ray, Aritra; Mukherjee, Soumalya; Das, Subhajyoti; Pal, Kunal; Das, Subhadeep; Karmakar, Parimal; Ray, Mitali; Ray, Sajal

doi:10.1016/j.ecoenv.2017.11.008

Cited by 72 publications

(28 citation statements)

References 33 publications

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“…Thus, they demonstrated certain coating-dependent variations in engineered nanomaterial toxicity to Eisenia fetida, which also changed after one year of soil ageing. Gautam et al [168] demonstrated that the copper sulfate and copper oxide nanoparticles severely influenced the characteristic immunological status of Metaphire posthuma. The treatment of copper oxide NP and copper sulfate led to a reduction in total coelomocyte density and phagocytic response of the coelomocyte of Metaphire posthuma, as shown in Figure 8.…”

Section: Copper-based Nanomaterialsmentioning

confidence: 99%

Recent Developments in the Application of Nanomaterials in Agroecosystems

Saleem

Zaidi

2020

Nanomaterials

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Nanotechnology implies the scientific research, development, and manufacture, along with processing, of materials and structures on a nano scale. Presently, the contamination of metalloids and metals in the soil has gained substantial attention. The consolidation of nanomaterials and plants in ecological management has received considerable research attention because certain nanomaterials could enhance plant seed germination and entire plant growth. Conversely, when the nanomaterial concentration is not properly controlled, toxicity will definitely develop. This paper discusses the role of nanomaterials as: (1) nano-pesticides (for improving the plant resistance against the biotic stress); and (2) nano-fertilizers (for promoting the plant growth by providing vital nutrients). This review analyzes the potential usages of nanomaterials in agroecosystem. In addition, the adverse effects of nanomaterials on soil organisms are discussed. We mostly examine the beneficial effects of nanomaterials such as nano-zerovalent iron, iron oxide, titanium dioxide, nano-hydroxyapatite, carbon nanotubes, and silver- and copper-based nanomaterials. Some nanomaterials can affect the growth, survival, and reproduction of soil organisms. A change from testing/using nanomaterials in plants for developing nanomaterials depending on agricultural requirements would be an important phase in the utilization of nanomaterials in sustainable agriculture. Conversely, the transport as well as ecological toxicity of nanomaterials should be seriously examined for guaranteeing its benign usage in agriculture.

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Section: Copper-based Nanomaterialsmentioning

confidence: 99%

Recent Developments in the Application of Nanomaterials in Agroecosystems

Saleem

Zaidi

2020

Nanomaterials

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“…Proteomic analysis was complementary for these observations. Indeed, the proteomic study shows that the proteins known as antioxidants in response to oxidative stress have been overexpressed by the rat organism namely carbonic anhydrase 3 [49,50], Glutathione S-transferase alpha-1 and Mu2 [51,52,53], catalase [20,39,54,55,56] and isocitrate dehydrogenase [57,58,59] to fight oxidative stress and recover under normal homeostatic conditions.…”

Section: Resultsmentioning

confidence: 99%

Effects of Iron Oxide Nanoparticles (γ-Fe2O3) on Liver, Lung and Brain Proteomes following Sub-Acute Intranasal Exposure: A New Toxicological Assessment in Rat Model Using iTRAQ-Based Quantitative Proteomics

Askri

Cunin

Ouni

et al. 2019

IJMS

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Iron Oxide Nanoparticles (IONPs) present unique properties making them one of the most used NPs in the biomedical field. Nevertheless, for many years, growing production and use of IONPs are associated with risks that can affect human and the environment. Thus, it is essential to study the effects of these nanoparticles to better understand their mechanism of action and the molecular perturbations induced in the organism. In the present study, we investigated the toxicological effects of IONPs (γ-Fe2O3) on liver, lung and brain proteomes in Wistar rats. Exposed rats received IONP solution during 7 consecutive days by intranasal instillation at a dose of 10 mg/kg body weight. An iTRAQ-based quantitative proteomics was used to study proteomic variations at the level of the three organs. Using this proteomic approach, we identified 1565; 1135 and 1161 proteins respectively in the brain, liver and lung. Amon them, we quantified 1541; 1125 and 1128 proteins respectively in the brain, liver and lung. Several proteins were dysregulated comparing treated samples to controls, particularly, proteins involved in cytoskeleton remodeling, cellular metabolism, immune system stimulation, inflammation process, response to oxidative stress, angiogenesis, and neurodegenerative diseases.

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“…In recent years, toxicity of various metal nanotoxins and inorganic salts were examined in earthworms. Immunological toxicity of copper nanoparticle and copper sulphate is in report [5] in a common variety of earthworm of India. Prior to toxicity analyses, physical characterization of copper oxide nanoparticle was carried out by dynamic light scattering, zeta potential, transmission electron microscopy, and EDAX Introductory Chapter: Earthworms -The Ecological Engineers of Soil http://dx.doi.org/10.5772/intechopen.78264…”

Section: A Farmer's Friendmentioning

confidence: 99%