Immunotherapy Combined With Chemotherapy and Radiotherapy for a Patient With Cancer of Unknown Primary: A Case Report

Abstract

Background: Cancer of unknown primary (CUP) is metastatic at diagnosis with unknown primary site, indicating a high degree of malignancy with poor prognosis. The development and application of targeted therapy and Immunotherapy is the current research hotspot, and provide more treatment options for CUP.Case Presentations: A 36-year-old freeworking male presented with pain on the right hip in April 2018. After various examinations, he was diagnosed as CUP. He received chemotherapy, immunotherapy and local radiotherapy in our department. However, the use of radiotherapy after immunotherapy resulted in severe pneumonia. Conclusions: Compared with traditional treatments, immunotherapy is effective treatment with fewer side effects and better patient tolerance. However, treating physicians should continue to pay special attention to the occurrence of side effects, when radiotherapy combined with immunotherapy.