Immunosuppressive therapy and kaposi's sarcoma after kidney transplantation

Moray, Gökhan; Başaran, Ö.; Yağmurdur, Mahmut Can; Emiroğlu, R; Bi̇lgi̇n, N; Haberal, Mehmet

doi:10.1016/j.transproceed.2003.11.016

Cited by 21 publications

(15 citation statements)

References 10 publications

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“…[323][324][325][326][327] In one study of 17 KS patients, it had antitumor activity in about half of those with classic and endemic KS and was generally well tolerated. 326 Imiquimod 5% cream may also be beneficial in the management of cutaneous AIDS-related KS.…”

Section: Immunotherapymentioning

confidence: 99%

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Kaposi sarcoma: A continuing conundrum

Schwartz

Micali

Nasca

et al. 2008

Journal of the American Academy of Dermatology

199

212

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Section: Immunotherapymentioning

confidence: 99%

“…316,335 In iatrogenic KS, the cessation of immunosuppressive therapy may be the most effective treatment, sometimes combined with chemotherapy. 136,145,288,324,325,336,337 Patients on immunosuppressive therapy, specifically corticosteroids and cytotoxic drugs, may have partial or complete regression when therapy is discontinued.…”

Section: Immunotherapymentioning

confidence: 99%

Kaposi sarcoma: A continuing conundrum

Schwartz

Micali

Nasca

et al. 2008

Journal of the American Academy of Dermatology

199

212

View full text Add to dashboard Cite

“…[4][5] It is seen in about 0.1% renal, liver, and cardiac transplant patients secondary to immunosuppressive treatment. [9][10][11][12][13] The development of a tumor is not directly related to the dose or the duration of steroid used. [14] Infection with HHV-8 is almost always required but not enough for the tumor development.…”

Section: Discussionmentioning

confidence: 99%

A Case of Kaposi's Sarcoma Following Treatment of Membranoproliferative Glomerulonephritis and a Review of the Literature

et al. 2007

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Kaposi's sarcoma (KS) is an unusual tumor principally affecting the skin of the lower extremities. Although the association between KS and renal transplant has been well documented, there are a few KS cases in the literature associated with membranoproliferative glomerulonephritis or other glomerular diseases. This report presents a patient with membranoproliferative glomerulonephritis (MPGN) who developed KS following treatment with long-term medium dose glucocorticoid and short-term additional immunosuppressives. The KS cases associated with glomerulonephritis are also reviewed. KS is a rare complication in glomerular diseases that may (or may not) be related to immunosuppression. Hence, immunosuppression treatment should be carefully planned in glomerulonephritis treatment and avoided if they are not essentially necessary.

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“…Consequently, it must be noted that this recommendation particularly applies to renal transplant recipients and may not apply to the same extent to other SOTRs. The second-line recommendation for the transplant physician is an overall reduction of the immunosuppressive regimen (recommendation D), which generally leads to resolution of iatrogenic KS [39,[44][45][46][47][48][49].…”

Section: Kaposi's Sarcomamentioning

confidence: 99%

“…Acitretin is a systemic retinoid beneficial in SCC prevention in the general population and in SOTRs, reducing SCC occurrence by 85% [41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56]. A significant effect against BCC has not been clearly documented in clinical studies and may relate to different retinoid sensitivity between BCC and SCC [57].…”

Section: Systemic Retinoid Therapymentioning

confidence: 99%