Immunosuppressive Action of Heat in Chickens

Rao, D. Subba; Glick, Bruce

doi:10.3181/00379727-133-34493

Cited by 37 publications

(11 citation statements)

References 4 publications

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“…Subba Rao and Glick (1970) confirmed the original finding that acute heating episodes limit humoral immune potential in chickens. Their experiments were designed to determine whether single or multiple heating exposures were more effective.…”

Section: Influence Of High Environmental Temperaturessupporting

confidence: 84%

Influence of Temperature on the Immune Response of Birds

Thaxton

1978

Poultry Science

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Section: Influence Of High Environmental Temperaturessupporting

confidence: 84%

Influence of Temperature on the Immune Response of Birds

Thaxton

1978

Poultry Science

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“…They suggested that corticosteroids were responsible for the effect. Similar results were shown by Subba Rao and Glick (1970; who found that heat exposure before SRBC immunization resulted in a decrease in haemagglutination titer, but when exposure was given after immunization no detrimental effect could be observed when sera were tested on the 5th and 7th day after immunization. They postulated that heat directly affected the peripheral lymphoid tissue and that the reticulo-endothelial activity was not impaired by heat treatment.…”

Section: Resultssupporting

confidence: 74%

Effect of Heat and Cold Stress on Humoral Immunity in Mice

Firouzi

Motamedifar

1999

Journal of Applied Animal Research

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“…It has been reported that both humoral (3,15,34,38,39) and cell-mediated (1 ,3 0 ,4 0 ) immune responses in different animal species are depressed by various types of stress. Moreover, impairment of antibody synthesis has been demon strated in cultures of spleen cells derived from donor mice exposed to stress prior to explantation of the spleen (9).…”

mentioning

confidence: 99%

Stress and the Hormonal Regulation of the Immune Response in Mice

Gisler¹

1974

Psychother Psychosom

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Exposure of mice to different types of acute stress (acceleration, ether anesthesia, restraint, overcrowding) or injection of adrenocorticotropic hormone resulted in an increase of plasma corticosteroid levels. This was associated with a decreased immune reactivity of their spleen cells in vitro. In contrast, after repeated exposure to ether stress, no immunosuppression was observed. Pretreatment of cell donors with diazepam prior to acute stress antagonized the immunosuppressive effect of restraint but was ineffective against the consequences of ether anesthesia. On the other hand, desipramine did not interfere with either type of stress response. Unresponsive spleen cell cultures could be reactivated by adding macrophages and B cells from normal mice. Addition of macrophages, B or T cells alone, or combinations of T cells with macrophages or B cells, had no restorative effect. Restraint stress significantly increased the homing of ⁵¹Cr-labeled lymph node cells from normal nu/+ mice (B and T cells) to spleen and bone marrow. In contrast, homing of nu/nu lymph node cells (B cells) to lymph nodes and spleen was decreased in stressed recipients, and an increased proportion of cells was found in the liver. Hypophysectomy of cell donors resulted in a persistent depression of immune responsiveness, which was restored by treatment with somatotropic hormone (STH). STH presumably accelerates recovery from stress-induced immunosuppression. Moreover, exogenous STH interfered with the effect of increased endogenous corticosterone.

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Immunosuppressive Action of Heat in Chickens

Cited by 37 publications

References 4 publications

Influence of Temperature on the Immune Response of Birds

Influence of Temperature on the Immune Response of Birds

Effect of Heat and Cold Stress on Humoral Immunity in Mice

Stress and the Hormonal Regulation of the Immune Response in Mice

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