Immunosensors for Assay of Toxic Biological Warfare Agents

Pohanka, Miroslav

doi:10.3390/bios13030402

Cited by 3 publications

References 102 publications

(101 reference statements)

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Nanomaterials and Quantum Dots for Electrochemical Sensing of Nitro-Aromatics-Based Explosives: A Short Review

Choudhury¹

2023

Surf. Rev. Lett.

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Explosives can be divided into low and high, the efficient detection of which is of utmost importance for security reasons. A major component of high explosives is the nitroaromatic compounds. These explosives, when sealed, have difficulty detecting. In this review work, the major techniques for explosive detection i.e. animal olfaction, calorimetric sensors, immunosensors, ion mobility spectrometry, and Raman spectroscopy are discussed. The materials or compounds comprising nitroaromatic sensors have been a topic of major research for the last three decades. Nanomaterials do provide an acceptable solution for portable, affordable, and efficient detection of analytes of explosive nature due to their redox properties. 3D nanomaterials like TiO2, Au, SiO2, Ag and CdSe-ZnS, 0D materials like CdSe, CdTe, ZnS and MoS2 can detect nitroaromatic compounds efficiently. In the upcoming technology, the incorporation of quantum dots is also considered for explosive detection. As an option for prospective research in the field, development in the use of boron nitride for detecting explosives is also a good option. A comprehensive review of such materials is discussed in this review paper.

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Nanomaterials and Quantum Dots for Electrochemical Sensing of Nitro-Aromatics-Based Explosives: A Short Review

Choudhury¹

2023

Surf. Rev. Lett.

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The biosafety incident response competence scale for clinical nursing staff: a development and validation study

Wu,

Zhang,

Zhang

et al. 2024

BMC Nurs

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Aims This study was designed to develop a biosafety incident response competence scale and evaluate its validity and reliability among clinical nurses. Design This study employed a sequential approach, comprising four phases: (1) the establishment of a multidimensional conceptual model, (2) the preliminary selection of the items, (3) further exploration and psychometric testing of the items, (4) the application of the scale among clinical nurses. Methods The biosafety incident response competence conceptual model was developed through literature review and the Delphi method. A total of 1,712 clinical nurses participated in the preliminary items selection, while 1,027 clinical nurses were involved in the further psychometric testing from July 2023 to August 2023. The item analysis, exploratory factor analysis and confirmatory factor analysis were conducted to evaluate the construct validity. Reliability was measured using Cronbach’s alpha, split-half reliability, and test-retest reliability, while validity analysis included content validity, structural validity, convergent validity, and discriminant validity. From September to November 2023, we conducted a survey using the established scale with a total of 4338 valid questionnaires collected. T-test and variance analysis was employed to determine potential variations in biosafety incident response competence based on participants characteristics. Results The final scale is composed of 4 factors and 29 items, including monitoring and warning abilities, nursing disposal abilities, biosafety knowledge preparedness, and infection protection abilities. The explanatory variance of the 4 factors was 75.100%. The Cronbach’s alpha, split-half reliability and test-retest reliability were 0.974, 0.945 and 0.840 respectively. The Scale-level content validity index was 0.866. The Average Variance Extracted of the 4 factors was larger than 0.5, the Construct Reliability was larger than 0.7, and the Heterotrait-Monotrait ratio were less than 0.9. There were significant differences in the scores of response competence among nurses of different ages, working years, titles, positions, departments, marital status and participation in biosafety training (all P < 0.05). Conclusions The biosafety incident response competence scale for nurses exhibits satisfactory reliability and validity, making it a valuable tool for assessing clinical nurses’ abilities in responding to biosafety incidents.

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Development and validation of the biosafety incident response competence scale for clinical nursing staff

Wu,

Zhang,

Zhang

et al. 2023

Preprint

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Aims: This study aimed to develop the biosafety incident response competence scale and evaluate its validity and reliability among clinical nurses. Design: A scale development and validation study was completed in the following three phases: (1) the construction of a multidimensional conceptual model, (2) the preliminary exploration of the items, and (3) further exploration and evaluation of the items. Methods: The multidimensional conceptual model was developed through a literature review and the Delphi method. A total of 1,712 clinical nurses participated in the preliminary item exploration, while 1,027 clinical nurses were involved in the further item evaluation from July 2023 to August 2023. The item analysis, exploratory factor analysis and confirmatory factor analysis were conducted to evaluate the construct validity. The reliability was measured by internal consistency, split-half reliability and test–retest reliability. Results: The final scale is composed of 4 factors and 29 items, scored on a 5-point scale. The factors included monitoring and warning abilities, nursing disposal abilities, biosafety knowledge preparedness, and infection protection abilities. The explanatory variance of the 4 factors was 75.100%. The validity and reliability of the scale are well validated. The internal consistency, split-half reliability and test-retest reliability were 0.974, 0.945 and 0.840 respectively. The scale has good structural validity and content validity. The content validity was 0.866. Conclusions: The biosafety incident response competence scale for nurses exhibits satisfactory reliability and validity, making it a valuable tool for assessing clinical nurses' abilities in responding to biosafety incidents. Patient or Public Contribution: Clinical nurses participated in the exploration and evaluation of the nurse's biosafety incident response competence scale.

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Immunosensors for Assay of Toxic Biological Warfare Agents

Cited by 3 publications

References 102 publications

Nanomaterials and Quantum Dots for Electrochemical Sensing of Nitro-Aromatics-Based Explosives: A Short Review

Nanomaterials and Quantum Dots for Electrochemical Sensing of Nitro-Aromatics-Based Explosives: A Short Review

The biosafety incident response competence scale for clinical nursing staff: a development and validation study

Development and validation of the biosafety incident response competence scale for clinical nursing staff

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