Abstract:Objective: to establish the features of the immune response in the early stages of diffuse toxic damage. Materials and methods. Diffuse toxic liver damage of male Wistar rats was caused by a single intraperitoneal injection of an oil solution of carbon tetrachloride (CCl4) at a dose of 50 mg/100 g. Animals were carried out from the experiment on days 3, 7 and 14. The study included hematological and histological analysis, immunohistochemical (IHC) staining of liver, thymus and spleen tissues, quantitative eva… Show more
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