Immunopathological and ultrastructural features in a case of papular elastorrhexis

Late onset of monomorphous flesh-colored papules of the neck

“…The pathogenic mechanism of this elastic tissue alteration is unknown, and no local inflammation, trauma or systemic associations have been described. A recent study suggests that abnormal fibroblasts might be involved (9). Differential diagnosis of PE includes perifollicular elastolysis, middermal elastolysis, pseudoxanthoma elasticum, pseudoxanthoma elasticum-like papillary dermal elastolysis, and white fibrous papulosis of the neck, like in our case.…”

Papular Elastorrhexis: A Case Report of Rare Connective Tissue Naevus

“…6 Given the resource limitations of unavailability of electron microscope, definitive confirmation with presence of degenerated elastic tissue from disorganized fibroblast is usually not applicable in our setting. 7 This limitation, highlights the importance of combined use of clinical and histopathological findings in the diagnosis of papular elastorrhexis and hence the timely counselling for expectant management. 5,6…”

Late onset of flesh‐colored papules of the neck

“…A recent study suggests that abnormal fibroblasts might be involved. 9 Differential diagnosis of PE includes perifollicular elastolysis, mid-dermal elastolysis, pseudoxanthoma elasticum, pseudoxanthoma elasticum-like papillary dermal elastolysis, and white fibrous papulosis of the neck.…”

“…The pathogenic mechanism of this elastic tissue alteration is unknown, and no local inflammation, trauma, or systemic associations have been described. A recent study suggests that abnormal fibroblasts might be involved 9 …”