Immunomodulatory properties of chicken cathelicidin-2 investigated on an ileal explant culture
Gábor Mátis,
Patrik Tráj,
Viktória Hanyecz
et al.
Abstract:As the threat posed by antimicrobial resistance grows more crucial, the development of compounds that can replace antibiotics becomes increasingly vital. Chicken cathelicidin-2 (Cath-2) belongs to the group of Host Defense Peptides (HDPs), which could provide a feasible solution for the treatment of gastrointestinal infections in poultry. It is a small peptide produced by the heterophil granulocytes of chickens as part of the innate immune response, and its immunomodulatory activity has already been demonstrat… Show more
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