Immunomodulatory measures to strengthen the body during Covid outbreak

Boharupi, Gauri; Shelotkar, Priyanka

doi:10.26452/ijrps.v11ispl1.3081

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…Therefore, it is necessary to follow noncoercive guidelines enforced by various enforcement agencies (18)(19)(20). Preventive measures are the only way to ensure safe survival in the lethal pandemic time and it will safeguard us from various other preventable disease (21)(22)(23).…”

Section: Precautionary Steps Available In Covid-19mentioning

confidence: 99%

COVID-19 and Its Current Trends with Long Term Implication

Mahadik¹

2021

pae

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BACKGROUND The coronavirus disease 2019 or COVID-19 is a serious medical threat that is posed before since more than a year. Scientists and researchers from all over the world are working on the solution on the ongoing problem. SUMMARY The mutated strain of the novel coronavirus has been successful in creating a buzz around the circuit of concerned people. The COVID-19 is being uncertain throughout its stay and any prediction would possibly go wrong. Long term implications may lack some major study but many lessons and parallels can be drawn from the previous similar outbreaks of SARS and MERS. CONCLUSION More fact based along with broad based study is needed to understand and correlate the COVID-19 and its long-term implications.

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Section: Precautionary Steps Available In Covid-19mentioning

confidence: 99%

COVID-19 and Its Current Trends with Long Term Implication

Mahadik¹

2021

pae

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“…[ [49,50]. Interesting studies related to immune responses in coronavirus infection were reported [51][52][53][54].…”

Section: Il-6 Inhibitorsmentioning

confidence: 99%

Cytokine Storm in Novel Corona Virus Disease (COVID-19)

Begum¹

2021

pae

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Coronavirus disease 2019 (COVID-19) is the latest global issue which has threatened the medical fraternity since its earliest reports on December 31, 2019 in Wuhan, China, and has had a negative impact on global healthcare systems disturbing every aspect of normal human life. COVID-19 infection is distinguished by scope of various epidemiological and pathological features, including high cytokine levels in the blood, leading to an uncontrolled abnormalityresponse known as “cytokine storm”. Accumulating evidence from various clinical trials and studies suggest that this cytokine storm is related with increased intensity of COVID‐19 leading to mortality. It is essential to urgently establish the immunopathogenesis of the COVID-19 cytokine storm in the search of proper therapy of COVID disease.In this review article we have discussed the presentcomprehension of the attributes of COVID-19 and the clinical features, immunopathological mechanisms, and management of the COVID‐19 induced cytokine storm, especially in severe cases. Various clinical trials in COVID-19 infected patientshas shown a strong evidence between cytokine production upregulation in severe and critical COVID-19 infected patients and mortality. Considering that the majority of cases of respiratory system and multiorgan failure are caused due to the continuous massive cytokine release, implementation of therapeutics that attenuate this overregulated inflammatory response can perhaps be a possible treatment for severe COVID-19 patients. Thus therapeutic methods for cytokine storm treatment in the pathology of severe COVID-19 infection warrant special attention. We have discussed the immunopathogenesis of severe COVID-19 infection and the induced cytokine storm and its. In addition, we explored treatment approaches to reverse overactive inflammation in severe COVID-19 infected patients.

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“…The lethal nature of the infection may provoke all sections of the society to protect themselves as there is no incentives in getting contracted by the infection (17). Few of the related studies on treatment aspects were reported (26,27).…”

Section: Way Forwardmentioning

confidence: 99%

COVID-19 and Most Affected Section of the Society

Rusia¹

2021

pae

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BACKGROUND COVID-19 or coronavirus disease 2019 is constantly emerging pandemic that has created unprecedented challenge in front of humanity as a whole. Extremely high spreading ability and high mortality rate and negative clinical outcomes is what mostly feared of. SUMMARY COVID-19 has affected almost every person directly or indirectly. The multispectral impact on human life is unprecedented. The differential impact on various strata of the society needed more vigorous study on it so that clear picture emerges out. The plight of migrant laborers and daily wagers were seen by many and consoled. The vulnerable section mentioned had negative effect on health, sociopolitical and economic aspect of their lives. More person are on the verge of extreme poverty than never before. CONCLUSION More philanthropic activity and poverty alleviating programs are needed to avoid widespread social distress among population. Sectional research and targeted delivery of schemes may be needed so that true beneficiary will get the benefit.

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Immunomodulatory measures to strengthen the body during Covid outbreak

Cited by 4 publications

References 6 publications

COVID-19 and Its Current Trends with Long Term Implication

COVID-19 and Its Current Trends with Long Term Implication

Cytokine Storm in Novel Corona Virus Disease (COVID-19)

COVID-19 and Most Affected Section of the Society

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