Immunomodulatory Effects of N-Acetyl Cysteine Treated SCAP

Limansubroto, Nerisa; Chung, Whasun O.; Johnson, James D.

doi:10.1016/j.joen.2022.05.005

Cited by 1 publication

(1 citation statement)

References 29 publications

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“…Other favorable effects of NAC are correlated to its immunomodulating activity as well as oxidative stress reduction, permitting an ability to maintain and improve the bladder mucosal protection. Although no studies have been conducted regarding the effects of NAC on bladder urothelial cells in terms of immunomodulation and reduction of oxidative stress, its effects on pulmonary and bronchial epithelium are well-known [ 61 , 62 , 63 ]. In particular, regarding concerns surrounding immunomodulation activity, UTIs involve complex interactions between the pathogen and the host immune system.…”

Section: N -Acetylcysteinementioning

confidence: 99%

Novel Key Ingredients in Urinary Tract Health—The Role of D-mannose, Chondroitin Sulphate, Hyaluronic Acid, and N-acetylcysteine in Urinary Tract Infections (Uroial PLUS®)

Crocetto,

Balsamo,

Amicuzi

et al. 2023

Nutrients

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Urinary tract infections represent a common and significant health concern worldwide. The high rate of recurrence and the increasing antibiotic resistance of uropathogens are further worsening the current scenario. Nevertheless, novel key ingredients such as D-mannose, chondroitin sulphate, hyaluronic acid, and N-acetylcysteine could represent an important alternative or adjuvant to the prevention and treatment strategies of urinary tract infections. Several studies have indeed evaluated the efficacy and the potential use of these compounds in urinary tract health. In this review, we aimed to summarize the characteristics, the role, and the application of the previously reported compounds, alone and in combination, in urinary tract health, focusing on their potential role in urinary tract infections.

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Section: N -Acetylcysteinementioning

confidence: 99%