Immunomodulation of salivary gland function due to cancer therapy
Ana C. Costa‐da‐Silva,
Carlos U. Villapudua,
Matthew P. Hoffman
et al.
Abstract:Functional salivary glands (SG) are essential for maintaining oral health, and salivary dysfunction is a persistent major clinical challenge. Several cancer therapies also have off‐target effects leading to SG dysfunction. Recent advances highlight the role of SG immune populations in homeostasis, dysfunction and gland regeneration. Here, we review what is known about SG immune populations during development and postnatal homeostasis. We summarize recent findings of immune cell involvement in SG dysfunction fo… Show more
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