Immunomodulating capacity of commercial fish protein hydrolysate for diet supplementation

Duarte, Júlio César; Vinderola, Gabriel; Ritz, Barry W.; Perdigón, Gabriela; Matar, Chantal

doi:10.1016/j.imbio.2005.12.002

Cited by 118 publications

(72 citation statements)

References 38 publications

(41 reference statements)

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“…The inclusion of FPH in diet may afford more sufficient digestible protein which could be impacted better into the immune system of fish. Furthermore, fish proteins are likely to contain a large amount of bioactive sequences and constitute a potential reservoir for potent immunomodulators (Duarte et al, 2006). Biologically active peptides with immunostimulating and antibacterial properties can be produced during the hydrolyzing procedure (Bøgwald et al, 1996;Kotzamanis et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

Effects of fish protein hydrolysate on growth performance and humoral immune response in large yellow croaker (Pseudosciaena crocea R.)

Tang

Zhao

et al. 2008

J. Zhejiang Univ. Sci. B

136

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Abstract:We investigated the effects of fish protein hydrolysate (FPH) on growth performance and humoral immune response of the large yellow croaker (Pseudosciaena crocea R.). One thousand and two hundred large yellow croakers [initial average weight: (162.75±23.85) g] were divided into four groups and reared in floating sea cages (3 m×3 m×3 m). The animals were fed with 4 diets: basal diet only (control) or diets supplemented with 5%, 10% and 15% (w/w) FPH. The results show that dietary FPH levels significantly influenced the growth and immunity of the large yellow croaker. Compared with the control group, total weight gain (TWG) in all treatment groups, relative weight gain (RWG) and specific growth rate (SGR) in fish fed with diets supplemented with 10% and 15% FPH were significantly increased (P<0.05). Similar results were observed in immune parameters [lysozyme activity, serum complements, immunoglobulin M (IgM)]. Lysozyme activity, complement C4 and IgM were also significantly increased (P<0.05) in fish fed with diets supplemented with 10% and 15% FPH, while complement C3 level was significantly increased (P<0.05) in all treatment groups. In general, with the supplementation of FPH, particularly at dose of 10%, the growth performance and immunity of the large yellow croaker can be improved effectively.

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Section: Discussionmentioning

confidence: 99%

Effects of fish protein hydrolysate on growth performance and humoral immune response in large yellow croaker (Pseudosciaena crocea R.)

Tang

Zhao

et al. 2008

J. Zhejiang Univ. Sci. B

136

View full text Add to dashboard Cite

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“…Fish protein, being different from other dietary proteins, is probably to contain many specific and potent bioactive subsequences in nutritional perspective for their competitive and aggressive living conditions (Kim and Mendis 2006;Duarte et al 2006). So if the potent bioactive compounds were extracted and the functions were revealed, it would open a new perspective for functional food development.…”

Section: Compositional Analysis Of Gphmentioning

confidence: 99%

The neuroprotective and antioxidant activities of protein hydrolysates from grass carp (Ctenopharyngodon idella) skin

Cai¹,

Wu²,

Lv³

et al. 2014

J Food Sci Technol

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To observe the neuroprotective and antioxidant activities of the grass carp protein hydrolysates (GPH) obtained from grass carp (Ctenopharyngodon idella) skin by enzymatic hydrolysis. GPH prepared using Protamex, at different (5, 10, 15, 20 and 30 %) degrees of hydrolysis (DH) were investigated. The DPPH radial scavenging, reducing power and inhibition of linoleic acid oxidation activities of GPH were significantly improved by a low DH (5 %) compared with those of GPH with a higher DH (p<0.05). A low degree of enzymatic hydrolysis was appropriate to obtain GPH with improved neuroprotective activities. These results suggest that the control of the DH may be an effective strategy to modify specific neuroprotective and antioxidant activities of GPH, and GPH has potential as a functional food ingredient for related functional and health benefits.

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“…Depuis quelques années, des actions plus HS23 physiologiques ont été trouvées. Une augmentation des taux d'IgA, signe d'un renforcement de l'immunité de la muqueuse, est observée chez la souris recevant des protéines de poisson fermentées non seulement au niveau de l'intestin, mais à distance dans les bronches, suggérant un passage des peptides et un effet systémique [11].…”

Section: Ré Sistance à L'insulineunclassified

“…Ces effets illustrent la synthèse in vitro de facteurs de croissance par des hydrolysats de poisson ou de crevettes [7,8]. Rappelons la stimulation de l'immunité muqueuse intestinale de la souris sous l'effet de protéines de poisson fermentées [11].…”

Section: Valeur Biologique Satié Té ; Intestinunclassified

Functional peptides from the sea

Bouglé

2007

Phytothérapie

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La digestion enzymatique des protéines de produits d'origine marine est susceptible de libérer des peptides possédant une action biologique. Plusieurs peptides de poissons, d'algues ou de crustacés ont été isolés. De nombreuses activités ont été mises en évidence, en particulier concernant la prévention des complications cardio-vasculaires et métaboliques de l'obésité (diminution de la tension artérielle, de la peroxydation, de la coagulation, du cholestérol, de la résistance à l'insuline), mais aussi le renforcement des défenses contre l'infection, la prévention du cancer. La valeur biologique des protéines et des peptides est bonne ; ils ont des effets distincts des autres sources azotées sur les sécrétions digestives et la satiété. Des études cliniques sont maintenant nécessaires pour confirmer ces résultats la plupart du temps obtenus par des études expérimentales. Mots clés : Peptides -Activité biologique -Produits de la merSyndrome métabolique -ImmunitéFunctional peptides from the sea Abstract: The enzymatic breakdown of marine proteins may yield biologically active peptides. A number of peptides have been isolated from fish, seaweed and crustaceans, and several of their properties have been uncovered, most notably concerning the prevention of the metabolic and cardiovascular complications of obesity (blood pressure, peroxidation, blood clotting, cholesterol levels, and insulin resistance), enhancement of immune defences and cancer prevention. These proteins and peptides have high biological value and specific effects on digestive secretions and satiety. Clinical studies are needed to confirm experimental results.

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Immunomodulating capacity of commercial fish protein hydrolysate for diet supplementation

Cited by 118 publications

References 38 publications

Effects of fish protein hydrolysate on growth performance and humoral immune response in large yellow croaker (Pseudosciaena crocea R.)

Effects of fish protein hydrolysate on growth performance and humoral immune response in large yellow croaker (Pseudosciaena crocea R.)

The neuroprotective and antioxidant activities of protein hydrolysates from grass carp (Ctenopharyngodon idella) skin

Functional peptides from the sea

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