Immunological investigations in post-traumatic granulomatous and non-granulomatous uveitis.

Rahi, A H; Morgan, G; Levy, I S; Dinning, W.J.

doi:10.1136/bjo.62.10.722

Cited by 26 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, SO with nongranulomatous inflammation is not uncommon. 15 Dalen–Fuchs nodules are semicircular nodules that are mainly composed of epithelioid cells and lymphocytes within the choroid. These nodules are present in one-third of SO patients; 16 , 17 however, we did not observe these nodules in our cases.…”

Section: Discussionmentioning

confidence: 99%

Sympathetic ophthalmia after vitreoretinal surgery: a report of two cases

Shen

Zhang

et al. 2021

J Int Med Res

View full text Add to dashboard Cite

Sympathetic ophthalmia (SO) is a panuveitis that usually occurs after trauma to one eye. We describe two cases of SO occurring after 23-gauge vitrectomy. Case 1 involved a 66-year-old woman who underwent pars plana vitrectomy (PPV) for a rhegmatogenous retinal detachment. Two months later, she presented with decreased visual acuity (VA) and bilateral uveitis. Case 2 involved a 43-year-old woman who underwent a second PPV for recurrent retinal detachment. Two months later, she presented with bilateral panuveitis. Both patients were diagnosed with SO and were treated with methylprednisolone and cyclosporine. The first patient was further treated with a dexamethasone intravitreal implant (Ozurdex®) owing to the side effects of methylprednisolone. The VA and symptoms improved significantly after treatment in both patients. Bilateral granulomatous panuveitis following PPV should alert surgeons to consider SO. Appropriate interventions for SO can produce positive outcomes.

show abstract

Section: Discussionmentioning

confidence: 99%

Sympathetic ophthalmia after vitreoretinal surgery: a report of two cases

Shen

Zhang

et al. 2021

J Int Med Res

View full text Add to dashboard Cite

show abstract

“…It was recently speculated that any photoreceptor antigen could be the offending antigen in sympathetic ophthalmia if antigen flow was directed so that immunologic suveillance would be encountered princi pally in the choroid [8,9,13]. This directionality to antigen flow would be imparted by phagocytosis of the outer segments and subsequent process ing by the retinal pigment eipithelium.…”

Section: Discussionmentioning

confidence: 99%

Retinal ‘s’ Antigen Disease in Rats

Marak¹,

Rao²

1982

Ophthalmic Res

View full text Add to dashboard Cite

The form of experimental allergic uveoretinitis induced by sensitization with retinal ‘s’ antigen in rats actually begins as a pars planitis and juxtapapillary choroiditis. Retinal inflammation develops at the middle limiting vascular layer of the retina and extends outward with focal destruction of photoreceptors and inward as a perivasculitis of small retinal vessels. Extensive choroiditis is a late development in severely diseased animals. Significant strain differences in susceptibility to disease were observed

show abstract

“…Such a classification, however, could be very difficult, especially for the type IV, involving mainly the T lymphocytes, because the cells obtained by punc ture are not numerous enough and in poor condition. Type I, where an IgE antibody combines with mast cells to allow the release of histamine and related substances, seemed unlikely in uveitis until an elevation of IgE was found by Rahi et al [1976] in the serum, and a questionable produc tion of the same in the eye itself by Hartmann et al [1977] in cases of uveitis. Finally, uveitis might involve one of the types II or III, although the role of various immunoglobulins and complement factors in that dis ease is not yet clear.…”

mentioning

confidence: 99%

Newer Immunological Studies of the Aqueous Humor in Uveitis

Martenet¹,

Kälin²,

Grob³

1980

Ophthalmic Res

View full text Add to dashboard Cite

Uveitis is a disease with rather non specific clinical aspects, a microbiological etiology being demonstrated only rarely. Assuming that uveitis could be the result of an nonspecific immunological disorder, the authors have studied the levels of various immunoglobulins in the aqueous humor in uveitis, anterior and posterior, as well as in noninflamed eyes of cataract patients. Their results show especially an increase of IgA and C3 in all types of uveitis and suggest that this disease could involve some IgA-related immunologic pathway.

show abstract

Immunological investigations in post-traumatic granulomatous and non-granulomatous uveitis.

Cited by 26 publications

References 12 publications

Sympathetic ophthalmia after vitreoretinal surgery: a report of two cases

Sympathetic ophthalmia after vitreoretinal surgery: a report of two cases

Retinal ‘s’ Antigen Disease in Rats

Newer Immunological Studies of the Aqueous Humor in Uveitis

Contact Info

Product

Resources

About