Immunologic and Microbiologic Profiles of Chronic and Aggressive Periodontitis Subjects

Rescala, Bruno; Rosalem, Wilson; Teles, Ricardo; Fischer, Ricardo Guimarães; Haffajee, A. D.; Socransky, S. S.; Gustafsson, Anders; Figueredo, Carlos Marcelo

doi:10.1902/jop.2010.090643

Cited by 70 publications

(97 citation statements)

References 35 publications

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“…www.intechopen.com Rescala et al (2010) reported similar microbiological and immunological parameters for subjects with chronic periodontitis and AgP who showed comparable periodontal disease severity. Herein we report dental management of an otherwise healthy patient diagnosed with generalized AgP and rapidly progressing bone loss throughout the mouth.…”

Section: Treatment Resultsmentioning

confidence: 87%

Interdisciplinary Treatment of Aggressive Periodontitis: Three-Dimensional Cone-Beam X-Ray Computed Tomography Evaluation

Yamaguchi¹,

Suzuki²,

Tomoyasu³

et al. 2012

Pathogenesis and Treatment of Periodontitis

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Section: Treatment Resultsmentioning

confidence: 87%

Interdisciplinary Treatment of Aggressive Periodontitis: Three-Dimensional Cone-Beam X-Ray Computed Tomography Evaluation

Yamaguchi¹,

Suzuki²,

Tomoyasu³

et al. 2012

Pathogenesis and Treatment of Periodontitis

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“…7 GCF is a complex biological fluid that contains a mixture of serum-derived and inflammatory proteins. 8 The constituents of GCF arise from a variety of sources, including microbial plaque, host cells, and serum-derived factors; thus, a number of biomarkers are available to examine in the GCF. 7,8 Matrix metalloproteinase-9 (MMP-9) is derived predominantly from monocytes and macrophages, and its levels in GCF are higher in patients with periodontitis; therefore, MMP-9 may serve as a biomarker of periodontal disease and aid in early detection of periodontitis.…”

Section: Introductionmentioning

confidence: 99%

“…8 The constituents of GCF arise from a variety of sources, including microbial plaque, host cells, and serum-derived factors; thus, a number of biomarkers are available to examine in the GCF. 7,8 Matrix metalloproteinase-9 (MMP-9) is derived predominantly from monocytes and macrophages, and its levels in GCF are higher in patients with periodontitis; therefore, MMP-9 may serve as a biomarker of periodontal disease and aid in early detection of periodontitis. 9 An intermediate mechanism that lies between bacterial stimulation and tissue remodeling is the production of cytokines.…”

Section: Introductionmentioning

confidence: 99%

Impact of orthodontic retainers on periodontal health status assessed by biomarkers in gingival crevicular fluid

Rody¹,

Akhlaghi²,

Akyalçın³

et al. 2011

The Angle Orthodontist

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Objective: To evaluate whether biomarkers of inflammation and periodontal remodeling are differentially expressed in the gingival crevicular fluid (GCF) of patients wearing different types of orthodontic retainers. Materials and Methods: Thirty-one adult subjects (17 men and 14 women with an age range of 20 to 35 years) were allocated to three different groups. Group 1 consisted of 10 patients wearing fixed retainers, group 2 included 11 patients using lower removable retainers, and group 3 comprised 10 patients without retainers (control). Periodontal health assessment and GCF collection were carried out at two sites per subject: the lingual side of a central lower incisor and the lingual side of a lower second premolar. Aliquots from diluted GCF were screened for the presence of biomarkers using a microarray technique. Results: Group 1 patients exhibited a higher percentage of sites with visible plaque in the incisor region than the other groups (P 5 .03); no differences were noted in gingival bleeding and probing depths. The median concentrations (pg/mL) of interferon-gamma and interleukin-10 were significantly higher in the premolar sites of patients in group 2 (P 5 .01 and P 5 .04, respectively), whereas the concentration of matrix metalloproteinase-9 was significantly higher at the incisors of patients wearing fixed retainers (P 5 .02). A significant difference between the two sites was seen only in group 2. Conclusions: The presence of different orthodontic retainers may promote specific alterations in the GCF composition. With retention periods potentially becoming longer, this finding may be of clinical significance. (Angle Orthod. 2011;81:1083-1089

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“…The disease could ultimately lead to the formation of periodontal pockets upon bone loss and apical migration of the junctional epithelium [3,4]. It is classified into aggressive periodontitis (AP) and chronic periodontitis (CP) [5,6].…”

Section: Introductionmentioning

confidence: 99%

Human leukocyte antigen associations and c-reactive protein levels in lebanese patients with aggressive periodontitis—HLA and CRP in aggressive periodontitis

Chakhtoura¹,

Souccar²,

Al-Akl³

et al. 2011

OJST

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Immunologic and Microbiologic Profiles of Chronic and Aggressive Periodontitis Subjects

Abstract: There were no statistically significant differences in the measured immunologic and microbiologic parameters between subjects with GCP and GAgP.

Cited by 70 publications

References 35 publications

Interdisciplinary Treatment of Aggressive Periodontitis: Three-Dimensional Cone-Beam X-Ray Computed Tomography Evaluation

Interdisciplinary Treatment of Aggressive Periodontitis: Three-Dimensional Cone-Beam X-Ray Computed Tomography Evaluation

Impact of orthodontic retainers on periodontal health status assessed by biomarkers in gingival crevicular fluid

Human leukocyte antigen associations and c-reactive protein levels in lebanese patients with aggressive periodontitis—HLA and CRP in aggressive periodontitis

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