1993
DOI: 10.1006/clin.1993.1092
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Immunologic Alterations in Patients with Sensorineural Hearing Disorders

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Cited by 25 publications
(12 citation statements)
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“…Indeed, it has been postulated that the hearing loss is associated with autoimmunity (43). Positive anti-Tg antibodies and thyroid-stimulating antibodies were found in PS patients by Friis et al (44), and Mayot et al (45) reported anti-thyroid as well as anti-cochlear antibodies in a group of 40 patients with progressive SNHL, suggesting a link between autoimmune inner ear disease and autoimmune thyroid disease. More studies are needed to establish the importance of these observations, but we postulate that in the two families presenting with pseudo-Pendred, the hearing loss may be linked to the thyroid disorder on an autoimmune basis.…”
Section: Discussionmentioning
confidence: 89%
“…Indeed, it has been postulated that the hearing loss is associated with autoimmunity (43). Positive anti-Tg antibodies and thyroid-stimulating antibodies were found in PS patients by Friis et al (44), and Mayot et al (45) reported anti-thyroid as well as anti-cochlear antibodies in a group of 40 patients with progressive SNHL, suggesting a link between autoimmune inner ear disease and autoimmune thyroid disease. More studies are needed to establish the importance of these observations, but we postulate that in the two families presenting with pseudo-Pendred, the hearing loss may be linked to the thyroid disorder on an autoimmune basis.…”
Section: Discussionmentioning
confidence: 89%
“…In 1964, more than 200 cases had been reported in the literature. Several authors have demonstrated the inadequacy of relying upon any one or combination of the characteristic facets of this syndrome in making an accurate diagnosis (Mayot, 1993). In 1958 the potassium perchlorate discharge proved to be a reliable diagnostic test for Pendred syndrome in individuals with congenital sensorineural deafness (Morgan & Trotter, 1958), and it seems that the test is still accepted by many as the gold standard for that purpose (Trotter, 1960).…”
Section: Discussionmentioning
confidence: 99%
“…Dr. Kinne's interpretation is largely based on Ki-67 staining using MIB-1 antibody. It has been shown that this antibody fails to label nonmitotic proliferating cells unless the tissue sections are treated with microwave irradiation (2). Since the technical details are not provided in Dr. Kinne's letter, we are unable to comment on the labeling efficiency of their method.…”
Section: To the Editormentioning
confidence: 93%