Immunolocalization of the Epstein-Barr nuclear antigen-1 in conjunctival squamous carcinomas and dysplasias

Epstein–Barr virus in breast cancer: artefact or aetiological agent?

“…Thus, Bonnet et al found EBNA1 by immunohistochemistry in nine tumours reported to be PCR positive 4 and Preciado et al found reactivity with the 2B4 reagent in 24/69 (35%) ductal breast carcinomas 19. The results of Grinstein et al using the 2B4 antibody and whole section PCR seemed to suggest that EBV is also present in other common epithelial malignancies, including those of the lung, colon, and prostate 20 and Restelli et al recently detected 2B4 immunoreactivity in conjunctival squamous carcinomas 21. However, these results should be interpreted with caution since we also detected nuclear staining with the 2B4 monoclonal antibody in breast tumour cells, but could not detect EBV DNA in these samples 15.…”

Investigation of Human Papillomavirus and Epstein-Barr Virus DNAs in Pterygium Tissue

“…Piras et al detected three unusual strains of HPV in pterygia, named type 52, 54, and 90 (11). The importance of the study was that the detected types were the same in (23). In addition, the presence of EBV has been convincingly demonstrated in lymphocytic infiltrations of conjunctiva (24,25).…”

Cancers in People with HIV and AIDS

“…CSSC has for some time been suspected as having an infectious origin. One reason for this is the sharp increase in the incidence of CSCC among patients infected with HIV (Restelli et al 2005 ;Chisi et al 2006 ), as well as in patients with other forms of immunodefi ciency, such as transplant recipients (Macarez et al 1999 ;Shelil et al 2003 ). CSCC has emerged as an HIV-associated cancer that is increasing in incidence in Uganda and other sub-Saharan African countries over the past two decades, and this increase has been particularly striking in the young and in women (Chisi et al 2006 ;Porges and Groisman 2003 ).…”