Immunoinformatics approach for designing a multi-epitope subunit vaccine against porcine epidemic diarrhea virus genotype IIA spike protein
Ella Sira,
Edward Banico,
Nyzar Odchimar
et al.
Abstract:Background:
Porcine epidemic diarrhea (PED), caused by the porcine epidemic diarrhea virus (PEDV), is associated with high mortality and morbidity rates, especially in neonatal pigs. This has resulted in significant economic losses for the pig industry. PEDV genotype II-based vaccines were found to confer better immunity against both heterologous and homologous challenges; specifically, spike (S) proteins, which are known to play a significant role during infection, are ideal for vaccine development.
Aim:
Th… Show more
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