“…Excessive fibrosis in organs causes fatal morbid conditions such as liver cirrhosis. TGF-P is also considered to be closely involved in hepatic fibrosis (7). The regulation system of TGF-/3 activation seems to be essential to avoid excessive fibrosis.…”
These findings suggest that VN and PAI-1 are related to the active form of TGF-beta and that it is possible that the plasmin cascade is present in the human liver.
“…Excessive fibrosis in organs causes fatal morbid conditions such as liver cirrhosis. TGF-P is also considered to be closely involved in hepatic fibrosis (7). The regulation system of TGF-/3 activation seems to be essential to avoid excessive fibrosis.…”
These findings suggest that VN and PAI-1 are related to the active form of TGF-beta and that it is possible that the plasmin cascade is present in the human liver.
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