Immunohistochemical evaluation of different filament proteins in human salivary glands.

Interlobular excretory ducts of mammalian salivary glands: Structural and histochemical review

“…It is not known at present if these inclusions are in some way correlated with either the ecology or behavior of this fossorial species. Crystalloids are present in the taller ED cells in the sublingual gland of the African multimammate rodent, Praomys natalensis (Toyoshima and Tandler, 1991), and in the Caselitz et al, 1981aCaselitz et al, , 1981bCaselitz et al, , 1986Burns et al, 1988;Dardick et al, 1988SG Mori et al, 1985bHosaka et al, 1985;Born et al, 1987;Geiger et al, 1987;Takai et al, 1988;Gustafsson et al, 1988;Lee et al, 1990;Mori, 1991;Hamakawa et al, 1999SM Nakai et al, 1985Leitner, 1987 Golden hamster SG Takai et al, 1985a;Mori et al, 1985a;Mori, 1991 EDs of the accessory submandibular glands of the longwinged bat, Miniopterus magnater (Tandler et al, 1997a). EDs in the parotid glands of seven species of fruit bats in the genus Artibeus resemble SDs in the same gland, but occasionally include one or several dark cells in a given sectioned duct (Fig.…”

Monoclonal antibodies against keratins bind to intercalated duct and ductal basal cells of normal salivary glands in paraffin sections.

“…1,5,6,7,8,10,11,13,16,17,18, and 19 keratins and molecular weights ranging from 40 KDs (no. 19) to 68 KDs (no.…”

“…Monoclonal keratin antibodies could detect nos. 1,5,6,7,8,10,11,13,16,17,18 Several types of monoclonal antibodies for keratin polypeptides have been reported to specifically react with single keratins or with a limited number and with keratins of different molecular weights. Keratin proteins have demonstrated that keratins can be separated into two classes, acidic and basic; and 19 different keratin polypeptides are distinguishable, (8,21).…”

“…Keratin proteins have demonstrated that keratins can be separated into two classes, acidic and basic; and 19 different keratin polypeptides are distinguishable, (8,21). Immunohistochemical findings on keratin distribution in human salivary glands have been obtained with the use of polyclonal antikeratin antiserum and some monoclonal antibodies (3,4,11,(14)(15)(16)(17), however no studies have appeared on the immunohistochemical detection of specific keratin polypeptides using monoclonal antibodies in the normal salivary glands.…”

Expression of S-100 protein, glial fibrillary acidic protein, neuron-specific enolase, and keratin in mixed tumors of skin.

“…Myoepithelial cells are known to contract and to promote secretory functions from acinar or terminal secretory structures, and actin protein has been detected in tumors (5,10). On the contrary, the biological properties of modified or neoplastic myoepithelial cells in tumor lesions, may have changes to those of myofibrous elements combined with epithelial characteristics, as evidenced by positive reactions for vimentin, desmin and keratin proteins (6).…”