Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection
Leila B. Giron,
Qin Liu,
Opeyemi S. Adeniji
et al.
Abstract:People living with HIV (PLWH) experience increased vulnerability to premature aging and inflammation-associated comorbidities, even when HIV replication is suppressed by antiretroviral therapy (ART). However, the factors associated with this vulnerability remain uncertain. In the general population, alterations in the N-glycans on IgGs trigger inflammation and precede the onset of aging-associated diseases. Here, we investigate the IgG N-glycans in cross-sectional and longitudinal samples from 1214 women and m… Show more
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