Immunogenic profiling of metastatic uveal melanoma discerns a potential signature related to prognosis
Jian Wang,
Miaomiao Liu,
Jiaxing Sun
et al.
Abstract:Background
Uveal melanoma (UM) is an aggressive intraocular malignant tumor. The present study aimed to identify the key genes associated with UM metastasis and established a gene signature to analyze the relationship between the signature and prognosis and immune cell infiltration. Later, a predictive model combined with clinical variables was developed and validated.
Methods
Two UM gene expression profile chip datasets were downloaded from TCGA a… Show more
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