Immunocytologic Findings in a Case of Vogt-Koyanagi-Harada Syndrome

Auditory and vestibular manifestations of Vogt–Koyanagi–Harada disease

“…2,3 Although the disease has been reported throughout the world, it is more prevalent in Asian individuals and certain Latin-American groups. 5 Immunocytological findings are consistent with a T-cell mediated disorder causing an autoimmune reaction to uveal and dermal melanocytes. Some authors favour a viral cause, whilst others consider cell-mediated autoimmune mechanisms against melanocytes to play a role in the pathogenesis.…”

Subretinal fibrosis and choroidal neovascularization in Vogt-Koyanagi-Harada syndrome

“…Histopathologic examination of the limited eyes with VKH has consistently described a predominance of T lymphocytes with occasional aggregates of B lymphocytes and macrophages [5,14]. It is possible that the cytokines, immunoglobulins, and inflammatory mediators produced by the infiltrating cells interact with retinal pigment epithelial cells, Müller cells, and choroidal fibrocytes to form the fibrotic tissue as a reparative response to the inciting inflammation [26].…”

Vogt-Koyanagi-Harada disease masquerading anterior ischaemic optic neuropathy

“…Sector filling defect in the disc on FA and altitudinal visual field defect are more compatible with AION. Whether AION was caused independently of VKH or inflammatory cells in the choroid4 caused circulatory disturbances is hard to determine because the patient was at high risk of circulatory disorders. But disturbed choroidal circulation by inflammatory cells in VKH3 may support the latter idea.…”