Immunoblotting of streptococcal antigens in guttate psoriasis

Wilson, AnneB; Clark, Ian M.; Heard, S.R.; Munro, D.D.; Kirby, J.D.T.

doi:10.1111/j.1365-2133.1993.tb15144.x

Cited by 11 publications

(7 citation statements)

References 17 publications

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“…The activation of the alternative complement pathway and cross‐reactivity between streptococcal M protein surface antigens and human epidermis may be associated with the initiation of clinical manifestation 18,19 . Clinical studies suggest that a clear history of upper respiratory infection was obtained in 19.2–86%, 2,14,20,21 and serological evidence of recent streptococcal infection was found in 54–93% 1,2,18–21 . In our study, history of previous upper respiratory infection were found in 20 of 36 patients (55.6%) and elevation of ASO titers in 23 (63.9).…”

Section: Discussionsupporting

confidence: 46%

“…18,19 Clinical studies suggest that a clear history of upper respiratory infection was obtained in 19.2-86%, 2,14,20,21 and serological evidence of recent streptococcal infection was found in 54-93%. 1,2,[18][19][20][21] In our study, history of previous upper respiratory infection were found in 20 of 36 patients (55.6%) and elevation of ASO titers in 23 (63.9). Williams et al 8 suggested that guttate psoriasis occurring after the streptococcal infection was a common preceding manifestation of chronic plaque psoriasis.…”

Section: Discussionmentioning

confidence: 99%

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Clinical course of guttate psoriasis: Long‐term follow‐up study

Jwa²,

Song³

et al. 2010

The Journal of Dermatology

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Guttate psoriasis, known to have a better prognosis than other types of psoriasis, shows rapid involution and longer remission, but its clinical course has barely been studied. The aim of this study was to determine the clinical course and to compare the clinical and laboratory features of guttate psoriasis. This is a retrospective study of 26 patients with guttate psoriasis. The patients were divided into two groups; the good one with complete remission and long remission for at least 1 year (group A) and the poor one with incomplete remission and progression into chronic plaque psoriasis (group B). Among 36 patients, 22 patients (61.1%) were group A and 14 patients (38.9%) were group B. In group A, most of the skin lesions disappeared within 8 months. In group B, two patients without proper treatment progressed to plaque psoriasis. The onset age was younger and more frequent upper respiratory infection and high anti-streptolysin O (ASO) titer were found in group A, but family history of psoriasis was more common in group B. Patients had two distingushable clinical courses: rapid involuting course with long-term remission and chronic course without remission. There was a tendency toward younger age of onset with elevated ASO titer in patients with rapid involuting course.

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Section: Discussionsupporting

confidence: 46%

Section: Discussionmentioning

confidence: 99%

Clinical course of guttate psoriasis: Long‐term follow‐up study

Jwa²,

Song³

et al. 2010

The Journal of Dermatology

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“…To identify the antigens of S. pyogenes recognized by the sera of psoriatic patients, Wilson et al 22 . studied by Western blot the response patterns of the sera of patients with guttate psoriasis and healthy subjects to streptococcal antigens of groups A, C and G. They did not find bands or patterns specific for any of the groups examined, but the guttate psoriatic group had both heavier and more numerous bands.…”

Section: Discussionmentioning

confidence: 99%

IgG class antibodies from psoriasis patients recognize the 60‐KDa heat‐shock protein of Streptococcus pyogenes

et al. 2004

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“…In this field, the most convincing evidence has been reported in the setting of the guttate type, which has been related to streptococcal pharyngeal infection on the basis of epidemiological and immunological studies, including the T-cell receptor specificities of lesional skin-infiltrating T cells [10,11,12,13,14]. Likewise, a case control study had suggested that recent pharyngeal infection was associated with a 7-fold increase in the risk of a first episode of guttate psoriasis compared with controls, but the study did not provide any information on the identification of infectious agents [15].…”

Section: Discussionmentioning

confidence: 99%

National Survey of Psoriasis Flares after 2009 Monovalent H1N1/Seasonal Vaccines

Sbidian

Eftekahri²,

Viguier³

et al. 2014

Dermatology

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Background: Psoriasis is a common chronic immune-mediated disease resulting from interactions of a genetic background with environmental triggering factors such as stress and infection. So far, there is very limited information available about the impact of vaccine stimuli on psoriasis course. Objective: To collect cases of psoriasis flares occurring after vaccination through a national survey. Methods: We investigated cases of onset or flare of psoriasis occurring within 3 months following the 2009 monovalent H₁N₁/seasonal vaccination during the campaign of the 2009-2010 flu seasons in France. Results: Ten patients, 6 men and 4 women with a median age of 44 years (range 9-88), were reported with a psoriasis of new onset (n = 7) or with a worsening of previously diagnosed psoriasis (n = 3) within a median time period of 8 days following vaccination. Nine of them presented with a mixed guttate/plaque clinical phenotype, and 1 showed 2 successive generalized pustular psoriasis (GPP) flares after 2 different vaccine injections. Conclusion: The short time interval between vaccination and onset of psoriasis flares, the lack of other triggers and the flaring sequence following 2 different vaccines in a GPP patient suggest a possible association between the 2009 monovalent H₁N₁/seasonal vaccination and psoriasis flaring in the collected cases. Nevertheless, the likely very low incidence of psoriasis following vaccination emphasizes the safe profile and the relevance of vaccination strategies in psoriasis patients, especially in candidates for immunosuppressive treatments.

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Immunoblotting of streptococcal antigens in guttate psoriasis

Cited by 11 publications

References 17 publications

Clinical course of guttate psoriasis: Long‐term follow‐up study

Clinical course of guttate psoriasis: Long‐term follow‐up study

IgG class antibodies from psoriasis patients recognize the 60‐KDa heat‐shock protein of Streptococcus pyogenes

National Survey of Psoriasis Flares after 2009 Monovalent H1N1/Seasonal Vaccines

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