Immunoassays for Extracellular Vesicle Detection via Transmembrane Proteins Using Surface Plasmon Resonance Biosensors
Jesus M. Lopez Baltazar,
Wenchao Gu,
Markéta Bocková
et al.
Abstract:Extracellular vesicles (EVs) are preeminent carriers of biomarkers and have become the subject of intense biomedical research for medical diagnostics using biosensors. To create effective EV-based immunoassays, it is imperative to develop surface chemistry approaches with optimal EV detection targeting transmembrane protein biomarkers that are not affected by cell-tocell variability. Here, we developed a series of immunoassays for the detection of EVs derived from mouse monocyte cells using surface plasmon res… Show more
Cancer-associated extracellular vesicles (EVs) are crucial biomarkers for cancer diagnosis due to their rich content of tumor cell information. To efficiently and accurately detect cancer-associated EVs, an electrochemical hydrogen peroxide...
Cancer-associated extracellular vesicles (EVs) are crucial biomarkers for cancer diagnosis due to their rich content of tumor cell information. To efficiently and accurately detect cancer-associated EVs, an electrochemical hydrogen peroxide...
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