Abstract:Background and Objectives: Despite widespread vaccination programs against pertussis, there has been a worldwide re- surgence of the disease in recent years. We aimed to investigate protein composition of outer membrane vesicles (OMV) of Bordetella pertussis (Bp) and to evaluate the immunogenicity of OMV antigens both in the vaccine and the dominant wild type strains in Iran.
Materials and Methods: The OMV were purified from both vaccine and wild type strains. The immunoreactivity of the OMVs was investi… Show more
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