Immunizing Norduz goats against inhibin

Abstract

Abstract:The objective of this study was to investigate the effect of active inhibin immunization on follicular development and prolificacy in Norduz goats. Two times inhibin α-subunit 1-32 porcine was used for preparation of vaccine. It was observed that goats were successfully immunized against inhibin, following ultrasonographic inspection and antibody binding test. High number of follicles were developed in immunized goats. But , active immunization does not improve prolificacy in Norduz goats.

Inhibin immunization in Norduz sheep

“…In the ewe, either active or passive immunization techniques may be used in order to contribute the negative feedback regulation of follicle stimulating hormone (FSH) release from pituitary gland (Terqui et al 1995). Inhibin immunization was applied in several species for improving prolificacy such as goat (Medan et al 2003, Cedden et al 2007 ewe (Wheaton et al 1992, Naqvi et al 2009 and cattle (Wood et al 1993, Konishi et al 1996. Active immunization against inhibin-based peptide immunogens can be effective in increasing the ovulation rate in non-prolific sheep breeds (Naqvi et al 2009).…”