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Keywords:Immunization Maternal determinants Dropout Non-adherence a b s t r a c t Problem considered: The risk of health problems from vaccine-preventable diseases is highest in those who experience barriers in accessing immunization services. These barriers could be cost, location, lack of awareness of immunization services and their health benefits or other limiting factors.Material & methods: The present study was conducted to identify the determinants of complete immunization status among children aged 12e23 months in urban slums of Varanasi in India. A modified WHO EPI cluster sampling method has been used for sample selection. Data on 384 children were collected using pretested questionnaire through house to house visit. Chi-square test, bivariate and multivariate logistic regression were used to assess the factors associated with complete immunization status in the urban slums of Varanasi. Results: Only 57.03% children have received the complete recommended immunization schedule under universal immunization program. Significant determinants of the complete immunization were maternal age (OR ¼ 1.86, 95% CI 1.54e3.23), parity less than three (OR ¼ 2.84, 95% CI 1.98e3.73), employment status of mother (OR ¼ 1.39, 95% CI 1.21e2.63) and mother's education higher than secondary level (OR ¼ 1.59, 95% CI 1.30e2.88).