Immunity waning after COVID vaccine booster <i>vs.</i> infection—better than expected

Khoury, Johad; Najjar‐Debbiny, Ronza; Elemy, Ameer; Jabbour, Adel; Haj, Juliana; Abu-Sini, Majdolen; Yasin, Rabah; Amin, Mohammad Ashraful; Hellou, Elias; Nasrallah, Najib; Saffouri, Amer

doi:10.1080/23744235.2022.2097304

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…However, the rate of reduction in antibody titres after a booster dose might be slower than after a second dose. 99 , 100 Our booster-dose data were compared with that of unvaccinated individuals and did not directly compare a booster dose with the primary series itself. Richterman and colleagues 79 found a baseline benefit of the two mRNA doses plus a booster dose compared with two mRNA doses (OR 0·34) for omicron infections that was only slightly decreased 112 days after booster dose (OR 0·45).…”

Section: Discussionmentioning

confidence: 99%

Long-term effectiveness of COVID-19 vaccines against infections, hospitalisations, and mortality in adults: findings from a rapid living systematic evidence synthesis and meta-analysis up to December, 2022

Wu¹,

Joyal‐Desmarais²,

Ribeiro³

et al. 2023

The Lancet Respiratory Medicine

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Section: Discussionmentioning

confidence: 99%

Long-term effectiveness of COVID-19 vaccines against infections, hospitalisations, and mortality in adults: findings from a rapid living systematic evidence synthesis and meta-analysis up to December, 2022

Wu¹,

Joyal‐Desmarais²,

Ribeiro³

et al. 2023

The Lancet Respiratory Medicine

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“…The COVID-19 vaccination campaign began in the UK in December 2020, reaching 150 million total doses across the first, second, spring, and autumn booster doses [21, 22]. The vaccination, in combination with high population infection attack rates over successive waves of SARS-CoV-2 incidence, has led to an increasingly complex picture of immunity, at individual and population levels, against SARS-CoV-2 infection [23, 24], which impacts syndromic surveillance efforts to understand the spatio-temporal infection burden.…”

Section: Introductionmentioning

confidence: 99%

Understanding the leading indicators of hospital admissions from COVID-19 across successive waves in the UK

Mellor,

Overton,

Fyles

et al. 2023

Epidemiol. Infect.

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Following the end of universal testing in the UK, hospital admissions are a key measure of COVID-19 pandemic pressure. Understanding leading indicators of admissions at the National Health Service (NHS) Trust, regional and national geographies help health services plan for ongoing pressures. We explored the spatio-temporal relationships of leading indicators of hospitalisations across SARS-CoV-2 waves in England. This analysis includes an evaluation of internet search volumes from Google Trends, NHS triage calls and online queries, the NHS COVID-19 app, lateral flow devices (LFDs), and the ZOE app. Data sources were analysed for their feasibility as leading indicators using Granger causality, cross-correlation, and dynamic time warping at fine spatial scales. Google Trends and NHS triages consistently temporally led admissions in most locations, with lead times ranging from 5 to 20 days, whereas an inconsistent relationship was found for the ZOE app, NHS COVID-19 app, and LFD testing, which diminished with spatial resolution, showing cross-correlation of leads between –7 and 7 days. The results indicate that novel surveillance sources can be used effectively to understand the expected healthcare burden within hospital administrative areas though the temporal and spatial heterogeneity of these relationships is a key determinant of their operational public health utility.

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An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals

Offersgaard¹,

Hernandez-Suarez²,

Feng³

et al. 2023

iScience

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Immunity waning after COVID vaccine booster vs. infection—better than expected

Cited by 3 publications

References 10 publications

Long-term effectiveness of COVID-19 vaccines against infections, hospitalisations, and mortality in adults: findings from a rapid living systematic evidence synthesis and meta-analysis up to December, 2022

Long-term effectiveness of COVID-19 vaccines against infections, hospitalisations, and mortality in adults: findings from a rapid living systematic evidence synthesis and meta-analysis up to December, 2022

Understanding the leading indicators of hospital admissions from COVID-19 across successive waves in the UK

An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals

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