Immune System Stimulation by Probiotic Microorganisms

Ashraf, Rabia; Shah, Nagendra P.

doi:10.1080/10408398.2011.619671

Cited by 413 publications

(272 citation statements)

References 111 publications

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“…The daily use of the probiotics Lactobacillus rhamnosus HN001 and Bifidobacterium lactis by the mother before delivery and during lactation showed significant increase in neonate cord blood cytokine (IFN-γ) as well as in IgA in breast milk [32]. A recent study showed a significant increase in phagocytic activity of blood leukocytes after three weeks of milk probiotics consumption or the consumption of probiotics-supplemented milk for nine weeks by healthy elderly persons.…”

Section: Probiotics and Immune Systemmentioning

confidence: 97%

“…A recent study showed a significant increase in phagocytic activity of blood leukocytes after three weeks of milk probiotics consumption or the consumption of probiotics-supplemented milk for nine weeks by healthy elderly persons. Also, it showed a significant increase of T lymphocytes and Natural Killer [32].…”

Section: Probiotics and Immune Systemmentioning

confidence: 98%

“…This immune reactions occurs without a noticeable harmful inflammatory response [31,32]. Lactobacillus and Bifidobacterium species are the most known bacteria included in such probiotics.…”

Section: Probiotics and Immune Systemmentioning

confidence: 99%

“…Lactobacillus and Bifidobacterium species are the most known bacteria included in such probiotics. It seems that the types and the doses of the bacterial strains are significant factors that may influence the host immune system [32]. Some Lactobacillus strains have shown to affect many aspects of the immune system and to suppress the inflammation associated with atherosclerosis, whereas, other strains of the same species like Lactobacillus species have proatherogenic role [31].…”

Section: Probiotics and Immune Systemmentioning

confidence: 99%

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Probiotics: Past, Present and Future Challenges

Altaha

Wadi

Shehabi

2018

int. arab. j antimicrob. agents

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The term probiotic is utilized to describe useful living microorganisms, intended to colonize the large intestine, when consumed in adequate amounts, they confer physiological health benefits to the host. In the last decade, probiotics have been widely used as a nutritional supplement and became a rapidly developing research topic that gained importance in medicine. Recent clinical trials have found that consumption of beneficial bacterial species can manipulate gut flora and reduce or prevent the development of certain serious diseases.

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Section: Probiotics and Immune Systemmentioning

confidence: 97%

Section: Probiotics and Immune Systemmentioning

confidence: 98%

“…This immune reactions occurs without a noticeable harmful inflammatory response [31,32]. Lactobacillus and Bifidobacterium species are the most known bacteria included in such probiotics.…”

Section: Probiotics and Immune Systemmentioning

confidence: 99%

Section: Probiotics and Immune Systemmentioning

confidence: 99%

See 2 more Smart Citations

Probiotics: Past, Present and Future Challenges

Altaha

Wadi

Shehabi

2018

int. arab. j antimicrob. agents

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“…Health benefits include: controlling gastrointestinal infections, improvement in lactose metabolism, anticarcinogenic and antimutagenic properties, reduction in serum cholesterol, and improvement in inflammatory bowel disease, Helicobacter pylori infections, and immune system stimulation [6].…”

Section: Introductionmentioning

confidence: 99%

Effect of Yogurt With or Without Probiotic Addition on Body Composition Changes and Immune System in an Obese Model

Maldonado-Galdeano¹

2017

FSN

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Yogurt is a dairy product made by milk fermented with Lactobacillus bulgaricus and Streptococcus thermophilus. Probiotic bacteria are added to conventional yogurt in order to boost benefits on the consumer health.In present work we studied in an obese mouse model the effect of the yogurt or probiotic yogurt supplementation to the diet on body weight, in biochemical parameters and in the thymus and intestinal immune system improvement. Adult mice received conventional balanced diet or a high-fat diet supplemented with milk, conventional yogurt or probiotic yogurt over 60 d. The body weight and biochemical parameters in serum (glucose, total LDL and HDL-cholesterol and triglycerides) were determined. Small intestine and thymus histology were analyzed. The changes in the gut microbiota, the possible translocation to internal organs and the levels of IgA and cytokines were also investigated. Probiotic yogurt was the most effective supplement for decreasing body weight and normalizing biochemical parameters in serum and in the improvement of small intestine and thymus histology. The gut microbiota showed increased bifidobacteria and recovered the balance of Enterobacteria population in obese mice given probiotic yogurt without translocation to internal organs, showing increases in IgA+ cells and cytokine production in gut. The present study demonstrated the safety and useful of yogurt consumption in obese host, benefiting mainly the innate mucosal immunity, biochemical parameters, intestine and thymus histology. These results allows advance in the research about the influence of functional foods on the thymus cells activity, which play a key role in the immune response.

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