2023
DOI: 10.1590/s1678-9946202365058
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Immune system gene polymorphisms associated with severe dengue in Latin America: a systematic review

Jorge Emilio Salazar Flórez,
Ángela María Segura Cardona,
Berta Nelly Restrepo Jaramillo
et al.

Abstract: One of the main challenges in the clinical management of dengue is the early identification of cases that could progress to severe forms of the disease. A biomarker that may enable this identification is the presence of genetic polymorphisms in genes associated with immune responses. The objective of this study was to perform a systematic review of the Latin American literature on these genes. An electronic literature search was carried out in PubMed, Scopus, Lilacs, and the Virtual Health Library, and referen… Show more

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