Immune stimulation and improved infection resistance in European sea bass (Dicentrarchus labrax) fed mannan oligosaccharides

Torrecillas, Silvia; Makol, Alex; Caballero, M. J.; Montero, Daniel; Robaina, L.; Real, Fernando; Sweetman, John; Tort, L.; Izquierdo, M.S.

doi:10.1016/j.fsi.2007.03.007

Cited by 293 publications

(271 citation statements)

References 31 publications

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“…In trials with Jian carp (Zhou and Li, 2004), common carp (Staykov et al, 2005) and rainbow trout (Staykov et al, 2007), the non-specific immune system was positively affected when MOS was used. Torrecillas et al (2007) reported dietary incorporation of 0.4% MOS activated sea bass immune system and increased its resistance to a bacterial infection directly inoculated in the gut. Vos et al (2010) observed immune-modulatory effect of GOS, FOS and pectin-derived acidic oligosaccharides during the early phase of a murine model.…”

Section: Immunitymentioning

confidence: 99%

Prebiotics: An Emerging Nutritional Approach for Improving Gut Health of Livestock and Poultry

Samal¹,

Behura²

2015

Asian J. of Animal and Veterinary Advances

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The complex interactions between diet, intestinal mucosa and intestinal microbiota affect health status in livestock and poultry. Various approaches have been tried to exploit this relationship for achieving maximum health benefits and supplementation of prebiotics constitutes one of them. Now a days prebiotics have become news mainly as an alternative to probiotics, which are difficult to handle in foodstuffs, but whose benefits to gut health are well established. Commercially available prebiotics are mostly inulin, fructo-oligosaccharides, mannan-oligosaccharides, galacto-oligosaccharides, transgalacto-oligosaccharides, lactulose and oligochitosan, etc. Prebiotics selectively stimulate the growth of Bifidobacterium sp., Lactobacillus sp. and certain butyrate producing bacteria and suppress the growth of toxogenic Escherichia coli, Clostridium perfringens, Streptococcus sp., peptococci, bacilli, Staphylococcus sp., Salmonella enteritidis, Campylobacter sp., bacteriodaeceae, pseudomonad, yeast and mould. Dietary supplementation of prebiotics improve a plethora of gut health attributes like hindgut fermentation, gut mucosal integrity, lipid and glucose homeostasis, mineral bio-availability and immune response in livestock and poultry owing to which many feed and pharma industries have been established. Their inclusion in diet can also suppress boar taint, control faecal odour, prevent colon cancer and reduce infestation of several parasites such as Ascaris sp., Trichuris sp. and Oesophagostomum dentatum. Their satietogenic effect results from decline in ghrelin secretion which in turn regulates body weight gain in obese animals. Prebiotics may eventually replace the role of antibiotics as growth stimulants in fishery, poultry and animal husbandry sectors. Because of all these multitude of benefits, inclusion of prebiotics in basal diet should be taken into consideration while preparing formula feed for livestock and poultry.

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Section: Immunitymentioning

confidence: 99%

Prebiotics: An Emerging Nutritional Approach for Improving Gut Health of Livestock and Poultry

Samal¹,

Behura²

2015

Asian J. of Animal and Veterinary Advances

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“…However, in these studies, feeding mannans and glucans-supplemented diets to common carp (C.carpio) enhanced growth and significantly improved feed utilization, antibody levels, bactericidal and lysozyme activity, and alternative complement pathway activity (Staykov et al 2005). In sea bass (D.labrax), incorporating mannans and glucans in the diet enhanced growth, activated immune response, and increased resistance to bacterial infection (Torrecillas et al 2007;Terova et al 2009b).…”

Section: Molecular Cloning and Expression Analysis Of Some Genes Invomentioning

confidence: 99%

“…The same effects also were observed for marine fish species. In the studies of Torrecillas et al (2007), the immune function improved after incorporating mannans and glucans in the diet of sea bass juveniles. Immune parameters, phagocytic activity of leukocytes, and bacterial activity of the sera in the mannans and glucans-fed sea bass groups showed significantly improved dose response when compared to the control group.…”

Section: Molecular Cloning and Expression Analysis Of Some Genes Invomentioning

confidence: 99%

Molecular cloning and gene expression analysis in aquaculture science: a review focusing on respiration and immune responses in European sea bass (Dicentrarchus labrax)

Terova

Rimoldi

Parisi

et al. 2012

Rev Fish Biol Fisheries

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Although fish farming has been practiced for 4,000 years, aquaculture research dates back only to about 1,870, whereas molecular techniques, in addition to the more traditional methods of biotechnology, were introduced only recently. Contemporary genomic approaches (often adapted from human or medical research) such as cDNA cloning and sequencing, cDNA microarray/expression analysis, and functional genomics, combined with improvements in transgenic technologies, have enhanced possibilities for aquacultural biotechnologists for improving fish growth rates and increasing resistance to pathogens and stressors.Although genomic technologies in fish have been applied primarily to model organisms, such as zebrafish (Danio rerio), fugu or pufferfish (Tetraodon nigroviridis), and medaka (Oryzias latipes), many teleosts of interest for biological research and with potential application in aquaculture have unique physiological characteristics that cannot be directly investigated from the study of small laboratory fish models. As a consequence, large-scale genomic research studies are increasingly being applied to farmed species of economic relevance, such as farmed rainbow trout, Atlantic salmon, tilapia, catfish, and sea bass. Accordingly, we describe the utilization of molecular cloning and gene expression analysis in cultured European sea bass (Dicentrarchus labrax) to generate ''transcriptomefocused'' information which may enable a better understanding of the transcriptional programs that underlie fish respiratory physiology and immune response pathways.

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“…Interestingly, with a concentrations of 25 mg/kg an increase in the total alginolyticus cohabitation challenge model produced a significant reduction in infected fish at doses of 2% and no infected fish were found at 4% of MOS [188].…”

mentioning

confidence: 98%

“…In this order several studies using different PAMPs as immunostimulants have been 508 reported. The most frequently studied have been diet additives derived from yeast cultures; by adding the 509 whole yeast [183][184][185][186], the yeast cell walls [187] and also extracts such as MOS [188], chitin [185,189],…”

mentioning

confidence: 99%

The response of fish to immunostimulant diets

Vallejos‐Vidal

Reyes-López

Teles

et al. 2016

Fish & Shellfish Immunology

264

110

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8 Fish Immunostimulation through dietary manipulation 9The aquaculture sector has shown a rapid growth over the last 30 years with an associated increase in 10 disease problems as result of rapid expansion and amongst other factors high stocking densities. In order 11to maintain fish health and to improve performance immunostimulants have been used as dietary 12 additives to improve weight gain, feed efficiency, and/or disease resistance in cultured fish. 13An immunostimulant is a natural or chemical substance that stimulates the immune system by specific 14(vaccines or antigens) or non-specific (irrespective of antigenic specificity) routes. In Aquaculture, non- 21The immunostimulant effect of dietary supplements in fish has been focused mainly on the evaluation of 22 non-specific immune parameters and, therefore, on the consequences of these treatments on the innate 23 immune system. The innate immune system has both cellular and humoral components by which it carries 24 out its protective function. The major components of the innate immune system at cellular level are 25 leukocytes, mainly monocytes, macrophages and granulocytes [1,2]. Among the granulocytes, neutrophils 26are the most abundant cell-type and their presence has been described in Salmoniformes, Cypriniformes 27 and Perciformes [3]. Neutrophils and macrophages are responsible for the production of bioactive 28 molecules for pathogen recognition and destruction, cellular communication and activation, initiation of 29 an adaptive immune response and later, resolution of an inflammatory response and tissue repair. 30Furthermore, these cell types are responsible in the majority for phagocytosis [4], one of the main 31 mediators of innate immunity to remove pathogens such as bacteria, viruses, and parasites. For this 32 reason, these immune cell types are also called phagocytes. This microbe/killing mechanism triggers 33 diverse antimicrobial processes that use a wide variety of mechanisms including cellular activation, 34 production of oxidative radicals, and the production of cytokines driving the inflammatory response 35 amongst others. 36Two of the most important antimicrobial systems of phagocytic cells are the NADPH phagocyte oxidase 37 and inducible nitric oxide synthase (iNOS) pathways, which are responsible for the generation of 38 superoxide (O2 − ) and nitric oxide (NO) radicals, respectively. NADPH oxidase, a multi-subunit complex, 39 catalyses a one-electron reduction of molecular oxygen into superoxide anion (O2 − ), also referred to as 40 reactive oxygen species (ROS), which is either spontaneously converted to H2O2 or enzymatically by 41 superoxide dismutase (SOD). In comparison to neutrophils, the size of the respiratory burst is much 42 reduced in macrophages [5]. Since O2 − is the first product to be released from the respiratory burst, the 43 measurement of O2 − has been accepted as a direct and accurate way of measuring respiratory burst 44 activity [6]: the reduction of ferricytochrome c to determine extracellular O2 − , and th...

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Immune stimulation and improved infection resistance in European sea bass (Dicentrarchus labrax) fed mannan oligosaccharides

Cited by 293 publications

References 31 publications

Prebiotics: An Emerging Nutritional Approach for Improving Gut Health of Livestock and Poultry

Prebiotics: An Emerging Nutritional Approach for Improving Gut Health of Livestock and Poultry

Molecular cloning and gene expression analysis in aquaculture science: a review focusing on respiration and immune responses in European sea bass (Dicentrarchus labrax)

The response of fish to immunostimulant diets

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