Immune profiles of pre-frail people living with HIV-1: a prospective longitudinal study
Lucy Kundura,
Renaud Cezar,
Sandrine Gimenez
et al.
Abstract:Background
People living with HIV (PLWH) are at risk of frailty, which is predictive for death. As an overactivity of the immune system is thought to fuel frailty, we characterized the immune activation profiles linked to frailty.
Methods
We quantified twenty-seven activation markers in forty-six virological responders (four females and forty-two males; median age, 74 years; median duration of infection, 24 years; median duration of undetectability… Show more
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