Immune-mediated haemolytic anaemia : possible association with Ancylostoma caninum infection in three dogs : case report

Abstract

Immune-mediated haemolytic anaemia (IMHA) may be primary or secondary. In primary IMHA, no underlying cause can be found, whereas secondary IMHA is triggered by an underlying cause, such as neoplasia, infectious diseases, or drugs. This paper describes 3 dogs with typical signs of IMHA that was possibly associated with the intestinal parasite <em>Ancylostoma caninum</em>. As intestinal helminths can be difficult to diagnose on faecal examination, it would be pertinent to performmultiple faecal examinations on any animal that has IMHA with no apparent underlying cause, as part of the therapy

Evaluation of Prognostic Factors and Establishment of a Prognostic Scoring System for Canine Primary Immune-Mediated Hemolytic Anemia

“…IMHA is distinguished between primary IMHA (pIMHA) and secondary IMHA (sIMHA) in the pathogenesis. The pIMHA is thought to be an idiopathic autoimmune disorder and the sIMHA is thought to be resulted from other diseases and conditions including neoplasia, infectious agents, drug exposure, other autoimmune diseases and vaccination [1,4,9,14,15,17,21].…”

Cerebral haemorrhage in a pregnant Standardbred mare with Evan's syndrome

“…The cause of Evan's syndrome in this case remains speculative; however, the potential role of intestinal parasites is intriguing. It has been postulated that Ancylostoma caninum infestation may have been associated with the development of IMHA in dogs (Lobetti and Schoeman 2001) and it is not unreasonable to assume that a similar pathophysiological process may have been implicated in the development of Evan's syndrome in this case, particularly in light of the fact that the Parascaris equorum infestation was associated with caseous lymphadenitis of a mesenteric lymph node.…”

Anemia Hemolítica Imunomediada Primária Em Cães - Revisão De Literatura

“…A AHIM secundária está relacionada a diversos agentes causadores, sendo os principais infecciosos (erliquiose, babesiose, leptospirose, dilofilariose, histoplasmose), neoplásicos (linfoma, hemangiossarcoma, leucemia linfoide, carcinoma pulmonar e gástrico, sarcoma), medicamentosos (sulfas, penicilinas, cefalosporinas, levamizol, dipirona, clorpromazina), defeitos intrínsecos (deficiência de fósforo, deficiência de piruvato e fragilidade osmótica hereditária) e variados (ingestão de alho e cebola, picada de abelha e vacinação) (BALCH; MACKIN, 2007). Infestação parasitária por Ancylostoma caninum também tem sido associada a AHIM secundária (LOBETTI;SCHOEMAN, 2001).…”