Immune layer of the population as an indicator of the activity of the epidemic process of hemorrhagic fever with renal syndrome in the Ulyanovsk region

Abstract

In order to detect antibodies to hantaviruses – pathogens of hemorrhagic fever with renal syndrome selectively over 2 periods: (80-90s of the 20th century and 2006-2016), the population of 21 districts of the region and the city of Ulyanovsk was examined. Sera were examined by indirect immunofluorescence (RNIF). The obtained results indicate changes in the loymopotential of natural foci of hemorrhagic fever with renal syndrome, which is confirmed by the indicators of the immune layer and the incidence of the population in the studied territories. It has been shown that the epidemic potential of natural foci of hemorrhagic fever with renal syndrome in the Ulyanovsk region is determined by the nature of the landscape. The risk of infection of the population is maximum in the zone of broad-leaved forests, minimal in the agricultural (steppe) landscape. Keywords: hemorrhagic fever with renal syndrome, immune layer, landscape.