Immobilizing CC chemokine receptor 4’s N-terminal extracellular tail on a capillary to study its potential ligands by capillary electrophoresis

Chen, Wenjing; Li, Meina; Yakufu, Pazilaiti; Ling, Xiaomei; Qi, Hui; Xiao, Junhai; Wang, Ying

doi:10.1016/j.ab.2011.12.033

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…The third approach is to immobilize the protein through a lock and key interaction, or ligand/receptor mechanism. 46…”

Section: Chemisorption Activated Adsorptionmentioning

confidence: 99%

Recombinant Protein-Based Nanoscale Biomemory Devices

Yagati¹,

Min²,

Jw³

2014

j. nanosci. nanotech.

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Biomolecular computing devices that are based on the properties of biomolecular activities offer a unique possibility for constructing new computing structures. A new concept of using various biomolecules has been proposed in order to develop a protein-based memory device that is capable of switching physical properties when electrical input signals are applied to perform memory switching. To clarify the proposed concept, redox protein is immobilized on Au nanoelectrodes to catalyze reversible reactions of redox-active molecules, which is controlled electrochemically and reversibly converted between its ON/OFF states. In this review, we summarize recent research towards developing nanoscale biomemory devices including design, synthesis, fabrication, and functionalization based on the proposed concept. At first we analyze the memory function properties of the proposed device at bulk material level and then explain the WORM (write-once-read-many times) nature of the device, later we extend the analysis to multi-bit and multi-level storage functions, and then we focus the developments in nanoscale biomemory devices based on the electron transport of redox molecules to the underlying Au patterned surface. The developed device operates at very low voltages and has good stability and excellent reversibility, proving to be a promising platform for future memory devices.

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“…The third approach is to immobilize the protein through a lock and key interaction, or ligand/receptor mechanism. 46…”

Section: Chemisorption Activated Adsorptionmentioning

confidence: 99%

Recombinant Protein-Based Nanoscale Biomemory Devices

Yagati¹,

Min²,

Jw³

2014

j. nanosci. nanotech.

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Applications of Biochromatography in the Screening of Bioactive Natural Products

Chen

Yang

Zuo

et al. 2013

Journal of Chromatographic Science

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Searching for bioactive compounds from natural resources such as plant materials has become a focus for study. Several models, such as animal (biofluid, organ and tissue) and cellular (several kinds of cell lines), have traditionally been used for this purpose. As a fast, economic and effective way to identify or predict bioactive compounds in complex matrices, biochromatography has developed rapidly during the past years. Combing the properties of traditional chromatography and biomaterials, biochromatographic analysis possesses features of simultaneous screening, separation and structural identification for active compounds in a complex matrix. According to the process, biochromatography can be divided into offline and online approaches. For offline bioextraction, the biomaterials are used as the extraction phase and followed by routine chromatographic analysis. For online biochromatography, the biomaterials are directly used as the stationary phase for chromatographic analysis. This paper reviews the applications of offline bioextraction followed by chromatographic analysis and online biochromatography, including molecular, cell membrane and cell, and artificial biomembrane chromatography in the screening or predicting active compounds from natural sources.

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Immobilizing CC chemokine receptor 4’s N-terminal extracellular tail on a capillary to study its potential ligands by capillary electrophoresis

Cited by 2 publications

References 31 publications

Recombinant Protein-Based Nanoscale Biomemory Devices

Recombinant Protein-Based Nanoscale Biomemory Devices

Applications of Biochromatography in the Screening of Bioactive Natural Products

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