Immobilization stress suppresses cutaneous delayed‐type hypersensitivity reaction induced by gastrointestinal sensitization in mice: association with Langerhans cell of the forestomach
Abstract:Psychological stress (PS) has various influences on allergic diseases. Although gastrointestinal sensitization induces hypersensitivity reactions in the skin, such as urticaria and dermatitis, due to food or drug allergy, the effect of PS on the gastrointestinal sensitization phase remains unclear. We administered 2,4,6‐trinitrochlorobenzene (TNCB) to BALB/c mice intragastrically (gastrointestinal sensitization). After 4 days, we elicited a cutaneous delayed‐type hypersensitivity (DTH) reaction by applying TNC… Show more
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